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EC number: 231-901-9 | CAS number: 7778-39-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
Additional information
Solubility and stability of Arsenic acid in water
The available data on arsenic acid indicate a high solubility of the substance with a value of 302 g/L in water. This means that the ranges of testing concentrations are far below the solubility limit of Arsenic in water.
Moreover, Henry’s law constant (H) quantifies the partitioning of chemicals between the aqueous phase and the gas phase.
For chemicals with H values less than 0.01 Pa m3/mole, the chemical is less volatile than water and as water evaporates the concentration of the chemical in the aqueous phase will increase; for chemicals with H values around 100 Pa m3/mole, volatilisation will be rapid.
For arsenic acid, the H value was calculated to be 0.868 Pa m3/mole at 25 °C (EUSES calculations based on the Vapour pressure = 1845 pa, water solubility = 302 g/L and mol. weight = 142 g/mol).
Therefore, based on his physico-chemical properties, Arsenic acid is not expected to volatilise.
Moreover, several in several studies the tested concentrations were measured analytically. The recoveries were quite high (more than 90%) indicating a good solubilisation of the test substance.
Based on these observations it can be concluded that the test substance arsenic acid stays in solution in water. Therefore the absence of concentrations monitoring is not invalidating for the aquatic studies.
Arsenic acid toxicity to aquatic organisms
A large set of data on aquatic toxicity of arsenic acid is available.
Large differences of toxicity were observed between the tested species. Individual studies as well as data reviews are available.
The validated references are listed in the table below.
Freshwater organisms
Species |
Test duration/ conditions |
Endpoint |
Result (mg/L) |
Reference |
Fish |
||||
Rainbow trout, juvenile Rainbow trout,alevin |
96 h 96 h |
LC50 LC50 |
= 67.5 > 360 |
Buhl KJ & Hamilton SJ (1990) |
Fathead minnow (Pimephales promelas) |
96h |
LC50 |
25.6 |
Eisler R (1988) |
Fathead minnow (Pimephales promelas) |
35 d |
LOEC NOEC |
1.9 0.97 |
Machado M.W |
Rainbow trout, juvenile
|
24 weeks |
NOEC |
13 µg As/g diet |
Cockell K.A (1991) |
Daphnia |
||||
Daphnia pulex |
96h |
LC50 |
3.4 |
Theegala, C. S. (2007) |
Daphnia magna |
96h |
NOEC |
44.66 mg/l (35.22-50.93) |
Fargasova A., (1994) |
Daphnia pulex |
21d |
NOEC |
> 1 |
Theegala, C. S. (2007) |
Daphnia pulex |
26d |
LOEC
NOEC |
0.020 arsenate = 10.5 arsenic 5 µg/L As |
Chen, CY (1999) cited in Lepper P., 2007 |
Algae and other aquatic plants |
||||
Scenedesmus obliguus |
96h |
EC50 |
0.159 |
Chen, F (1994) cited in Lepper P., 2007 |
Asterionella |
24 d |
NOEC |
0.160 |
ConwayHL (1978) |
Ankistrodesmus falcatus |
14 d |
EC50 NOEC |
0.256 0.01 |
Vocke, R.W. (1980) |
Scenedesmus obliquus |
14 d |
LC50 |
0.048 |
Vocke, R.W. (1980) |
Selenastrum capricornutum |
14 d |
LC50 NOEC |
30.7 12 |
Vocke, R.W. (1980) |
Microorganisms |
||||
Pseudomonas putida |
16h |
EC10 |
6.75 |
Bringmann, G (1976) |
Marine organisms
Species |
Test duration/ conditions |
Endpoint |
Result (mg/L) |
Reference |
|
|
|
|
|
Sheepshead minnow (cyprinodon vertegatus) |
96 h |
LC50 NOEC |
28 13 |
Lelievre, M.K. (1990) |
Mysid shrimp (Mysidopsis bahia) |
96h |
LC50 |
2 |
Lelievre, M.K. (1990) |
Strongylocentrotus purpuratus |
48 h |
LOEC EC10 |
0.011 0.006 |
Garman(1997) cited in Lepper P., 2007 |
Skeletonema costatum |
6 d |
LOEC |
0.013 |
Sanders J.G. (1979) cited in Lepper P., 2007 |
Conclusion:
The available toxicity data on freshwater and marine organisms belong to the same growth order. The lowest long term data belong to the range 5-10 µg/L and were observed on invertebrate and algae species.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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