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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 231-901-9 | CAS number: 7778-39-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The chronic toxicity of Disodium arsenate hepathydrate to Oncorhynchus mykiss (juveniles) was studied under flowthrough conditions. Three experiments were conducted. Juveniles were continuously exposed to control, and test chemical via semi-purified test diet supplemented with DSA. The diet was supplemented with 0, 10, 50, 90, 130 or170 µgAs/g diet in experiment 1, with 0, 50 or 100 µgAs/g diet in experiment 2, and with 0, 2.5, 5, 10, 25 or 50 µgAs/g diet in experiment 3. Observations were made on the physiological, histopathological and behavioural effects. The MATC was 13 to 33 µg As/g diet. As a worst case it can be considered as a LC10.
This study is classified as acceptable and satisfies with the guidelines requirements for an acute toxicity study with freshwater invertebrates.
This is the most severe result of the data set.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 13 µg/L
Additional information
Beside the key study, another reference is available on fish long-term toxicity.
The 35d chronic toxicity of Arsenic acid to Pimephales promelas(embryos and larvae) was studied under static conditions. Embryos were continuously exposed to control, and test chemical at measured concentrations in mg a.i/L of: 0.46, 0.97, 1.9, 3.4, 6.3 and 13 mg/l. Observations were made on the survival of organisms at hatch and on the survival and growth (wet weight and total length) of larvae after 30 days (post-hatch) of exposure. The 35d-NOEC was 0.97 mg a.i/L, based on the measured concentrations.
This study is classified as acceptable and satisfies with the guidelines requirements for an acute toxicity study with freshwater invertebrates.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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