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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 202-849-4 | CAS number: 100-41-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of ammonia comsumption was used as parameter for toxic inhibition of Nitrosomonas by ethylbenzene and the 24 hour EC50 was 96 mg/l.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 96 mg/L
Additional information
The inhibition of ammonia consumption was used as parameter for toxic inhibition of the nitrifying organism, Nitrosomonas, by ethylbenzene and the 24 hour EC50 was 96 mg/L.
Ethylbenzene was evaluated in activated sludge, respiration inhibition test using an activated sludge (domestic) in two separate studies. In the 1st study, the test procedure was designed to mimic the standard ATA using heterotrophic cultures under aerobic conditions. All tests were carried out in sealed serum bottles to prevent the loss of volatile chemicals. The inhibition of oxygen uptake was determined as criterion for the toxic inhibition of the aerobic activated sludge under the conditions of the study, the EC50 was 130 mg/L. In a second study ethylbenzene was evaluated in activated sludge, respiration inhibition test using an activated sludge (domestic) and under the conditions of the study, the EC50 was around 600 mg/L.
Anaerobic toxicity assays (ATA) were conducted using an enrichment culture that had been maintained in the laboratory. Under the conditions of the test, the 48 hour EC50 was 160 mg/L.
Along with the key study, 12 supporting studies have been included or the toxicity of ethylbenzene to microorganisms together with 6 studies considered unreliable (Klimisch score 3).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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