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Diss Factsheets
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EC number: 202-849-4 | CAS number: 100-41-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to other aquatic organisms
Administrative data
- Endpoint:
- toxicity to other aquatic vertebrates
- Type of information:
- other: Publication
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well-documented publication
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxic effects of endocrine disruptors on freshwater sponges: common developmental abnormalities
- Author:
- Hill, M. et al.
- Year:
- 2 002
- Bibliographic source:
- Environmental Pollution 117:295-300
Materials and methods
- Principles of method if other than guideline:
- Method: other
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Ethylbenzene
- EC Number:
- 202-849-4
- EC Name:
- Ethylbenzene
- Cas Number:
- 100-41-4
- Molecular formula:
- C8H10
- IUPAC Name:
- ethylbenzene
- Details on test material:
- IUCLID4 Test substance: other TS
Ethylbenzene
CAS No. 100-41-4
Purity: no data
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
Not applicable
Sampling and analysis
- Analytical monitoring:
- not specified
- Details on sampling:
- No data
Test solutions
- Vehicle:
- not specified
- Details on test solutions:
- No data
Test organisms
- Test organisms (species):
- other: other: freshwater sponge - Heteromyenia species and Eunapius fragilis
- Details on test organisms:
- No data
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 9 d
- Post exposure observation period:
- No data
Test conditions
- Hardness:
- No data
- Test temperature:
- No data
- pH:
- No data
- Dissolved oxygen:
- No data
- Salinity:
- No data
- Nominal and measured concentrations:
- 0.03, 0.3 and 3 mg/l
- Details on test conditions:
- According to the author, no official standards mentioned.
The toxic effect of ethylbenzene was examined on growth and development of two species of freshwater sponge, Heteromyenia spec. and Eunapius fragilis.
Test concentrations: 0.03, 0.3 and 3 mg/l
Obeservation period: 3, 6 and 9 days - Reference substance (positive control):
- not specified
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 9 d
- Dose descriptor:
- EC100
- Effect conc.:
- 3 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: germination
- Duration:
- 9 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 0.3 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: abnormal growth
- Details on results:
- At 0.3 mg/l abnormal growth in Heteromyenia species was observed. Sponges initiated germination, but produced a tight cluster (or tube) of cells that seemed to be exuded from the gemmule. Germination was completely inhibited at 3 mg/l
- Results with reference substance (positive control):
- No data
- Reported statistics and error estimates:
- No data
Any other information on results incl. tables
None
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- At 0.3 mg/l abnormal growth in Heteromyenia species was observed. Sponges initiated germination, but produced a tight cluster (or tube) of cells that seemed to be exuded from the gemmule. Germination was completely inhibited at 3 mg/l
- Executive summary:
The toxic effect of ethylbenzene was examined on growth and development of two species of freshwater sponge, Heteromyenia spec. and Eunapius fragilis.Test concentrations: 0.03, 0.3 and 3 mg/l Obeservation period: 3,6 and 9 days.
At 0.3 mg/l abnormal growth in Heteromyenia species was observed. Sponges initiated germination, but produced a tight cluster (or tube) of cells that seemed to be exuded from the gemmule. Germination was completely inhibited at 3 mg/l
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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