Didecyldimethylammonium chloride

Vapour pressure

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From March 15, 2012 to March 16, 2012

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: by loss of weight or by trapping vaporisate

Key result

Temp.:

ca. 20 °C

Vapour pressure:

< 0.002 Pa

Key result

Temp.:

ca. 20 °C

Vapour pressure:

< 0 mm Hg

Key result

Temp.:

ca. 25 °C

Vapour pressure:

< 0.006 Pa

Key result

Temp.:

ca. 25 °C

Vapour pressure:

< 0 mm Hg

Formulas Used:

Evaporation rate: (νT) =Dm/ F x t [g/cm /h]

where:

Dm = weight loss of the test substance [g]

F = surface of the sample plate [cm2]

t = elapsed time for the weight loss [h]

 

Vapour pressure equation log PT=c lognT+d

where:

c = constant specific for the experimental arrangement

d = constant specific for the experimental arrangement

 

Vapour pressure regression curve log PT=a 1/T+b

where:

T = temperature [K]

a = slope [K]

b = intercept

Results:

The isothermal TGA effusion method was applied for the determination of the vapour pressure of Didecyldimethylammonium chloride (DDAC). The vapour pressure of the test substance at 20°C (293K) and 25°C (298K) was:

	20°C		25°C
	[Pa]	[mmHg]	[Pa]	[mmHg]
Test substance	< 1.5 x 10^-3	< 1.1 x 10^-5	< 5.8 x 10-^3	< 4.3 x 10^-5

Conclusions:

Under the conditions of the study, the vapour pressure of test substance was found to be <1.5 × 10(-3) Pa = <1.1 × 10(-5) mm Hg at 20°C and <5.8 × 10(-3) Pa = <4.3 × 10(-5) mm Hg at 25°C.

Executive summary:

A study was conducted to determine the vapour pressure of DDAC according to the isothermal thermo gravimetric effusion method (OECD Guideline 104, EU method A.4 and US EPA OPPTS 830.7950). Approximately 11.1 or 15.8 mg of the test substance was applied to the surface of a roughened glass plate as a homogeneous layer. The plates were dried at 30°C under nitrogen in the thermogravimetric analyzer (TGA). The weight loss of the test substance was measured continuously as a function of time. Benzo(ghi)perylene, chrysene, hexachlorobenzene, naphthalene and water were used as reference substances for validation. The log Vt, 20 value which was obtained by extrapolation of the evaporation rate curve, fitted in the vapour pressure regression curve. Under the conditions of the study, the vapour pressure of test substance was found to be <1.5 × 10(-3) Pa = <1.1 × 10(-5) mm Hg at 20°C and <5.8 × 10(-3) Pa = <4.3 × 10(-5) mm Hg at 25°C.

Reference 2

Endpoint:

vapour pressure

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

supporting study

Study period:

Not applicable

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Remarks:

Data estimated by mpbpwin v1.43

Qualifier:

according to guideline

Guideline:

other: REACH guidance on QSARs: Chapter R.6. QSARs and grouping of chemicals

GLP compliance:

no

Type of method:

other: estimated by calculation

Key result

Temp.:

ca. 25 °C

Vapour pressure:

ca. 0 Pa

Remarks on result:

other: Estimated by calculation (Modified Grain Method)

Key result

Temp.:

ca. 25 °C

Vapour pressure:

ca. 0 Pa

Remarks on result:

other: Estimated by calculation (Modified Grain Method, sub-cooled liquid)

Estimated by calculation

Conclusions:

The vapour pressure of the test substance was estimated using mpbpwin v1.43 to be in the range of 9.44 10-9 Pa (Modified Grain Method, 25°C) to 4.79 10-7 Pa (Modified Grain method, 25°C, subcooled liquid).

Executive summary:

The vapour pressure of the test substance was estimated using mpbpwin v1.43 to be in the range of 9.44 10-9 Pa (Modified Grain Method, 25°C) to 4.79 10-7 Pa (Modified Grain method, 25°C, subcooled liquid).

Description of key information

The vapour pressure of the test substance was measured according to the isothermal thermo gravimetric effusion method of OECD Guideline 104, EU Method A.4 and US EPA OPPTS 830.7950 (Brekelmans, 2012).

Key value for chemical safety assessment

Vapour pressure:

0.006 Pa

at the temperature of:

25 °C

Additional information

- The vapour pressure was found to be <1.5 × 10-3 Pa (i.e. <1.1 × 10-5 mm Hg) at 20°C and <5.8 × 10-3 Pa (i.e. <4.3 × 10-5 mm Hg) at 25°C.

- Data presented in the DDAC assessment report for Product Type 8 conducted under Directive 98/8/EC (evaluating Competent Authority: Italy, June 2015, attached in Section 13 of the IUCLID dataset) reported an additional vapour pressure study with VP values of 5.9E-06, 1.1E-05 and 2.3E-04 at 20, 25 and 50ºC respectively (US ISC).

As a conservative approach, the relatively higher vapour pressure value <5.8 × 10-3 Pa at 25°C of the purified form of the registered substance has been considered further for hazard/risk assessment.