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Diss Factsheets
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EC number: 201-983-0 | CAS number: 90-30-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Sediment toxicity
Administrative data
Link to relevant study record(s)
- Endpoint:
- sediment toxicity: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well documented publication which meets basic scientific principles
- Qualifier:
- according to guideline
- Guideline:
- other: Cushman, R.M and McKamey, M.I., 1981, A Chironomus tentans bioassay for testing synthetic fuel products and effluents, with data on acridine and quinoline, Bulletin of Environmental Contamination and Toxicology 26, 601-605
- GLP compliance:
- no
- Analytical monitoring:
- yes
- Vehicle:
- yes
- Details on sediment and application:
- PREPARATION OF SPIKED WATER
- Details of spiking: Chemical added in excess to well water (pH 7.8, hardness 120-140 mg CaCO3/L), stirred overnight and filtered though Whatman paper #41
- Chemical name of vehicle (organic solvent, emulsifier or dispersant): Methanol
- Concentration of vehicle in test medium (stock solution and final test solution): 1 mg/L - Test organisms (species):
- Chironomus dilutus (previous name: Chironomus tentans)
- Details on test organisms:
- TEST ORGANISM
- Common name: midge
- Age of parental stock (mean and range, SD): fourth-instar larvae
ACCLIMATION
- Acclimation period: 24 hours - Study type:
- laboratory study
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Duration:
- 48 h
- Exposure phase:
- total exposure duration
- Hardness:
- 140 mg CaCO3/L
Alkalinity: 120 mg CaCO3/L - Test temperature:
- 23-26 °C
- pH:
- 7.8
- Dissolved oxygen:
- Begin: 8.5 mg/L
- Ammonia:
- not specified
- Nominal and measured concentrations:
- Nominal: four concentrations (not specified)
Measured after 48 hours: 65 to 90% of initial concentration - Details on test conditions:
- TEST SYSTEM
- Test container (material, size): 100 mL beaker covered with aluminium foil
- Overlying water volume: 100 mL
- Aeration: no
EXPOSURE REGIME
- No. of organisms per container (treatment): 7
- No. of replicates per treatment group: 4
- No. of replicates per control / vehicle control: 4
OVERLYING WATER CHARACTERISTCS
- Type of water (e.g. deionized, ground water, sea water, Elendt medium acc. to OECD 219):
- Source of water (if non-standard medium)
- Location: well water
- Alkalinity: 120 mg CaCO3/L
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : Mortality
VEHICLE CONTROL PERFORMED: yes - Reference substance (positive control):
- no
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 2.81 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: 2.55-3.12
- Reported statistics and error estimates:
- Control response corrected by Abbot's formula (1925), log transformation of and probit analysis (Finney 1978), data which were pi=0 or pi=1 were approximated by Berkson's formula (1953), weighted least-squared analysis of the transformed variables was used to fit data into linear regression model (Neter and Wasserman 1974), SAS software package was used (Barr et al. 1979)
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Naphthalene showed to be toxic to Chironomus tentans in a bioassay screening the acute toxicity (48h) of the test substance.
Reference
Description of key information
LC50(48h) = 2.81 mg/L (nominal, vehicle) for Chironomus tentans (read across)
Key value for chemical safety assessment
Additional information
No data are available for the toxicity of N-phenyl-1-naphthylamine to sediment organisms. Therefore, information from a supporting, structurally analogue compound (naphthalene) was taken into account.
In this key study, the toxicity of naphthalene (purity not stated) to Chironomus tentans was tested according to the method described by Cushman & McKamey (1981) in an aqueous medium (Millemann et al. 1984). Four concentrations were tested, with methanol as solvent (final concentration of methanol in the test solution 1 mg/L). As a result, the LC50 (48h) was determined to be 2.81 mg/L (mortality) with confidence limits of 2.55 to 3.12 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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