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EC number: 247-722-4 | CAS number: 26471-62-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
TDI is hydrolytically unstable. It can have only a transient existence in aqueous media. A water solubility value of 124 mg/l has been estimated (West et al, 2008) using a broadly accepted program, though a water solubility value for TDI is only a notional concept.
Key value for chemical safety assessment
- Water solubility:
- 124 mg/L
- at the temperature of:
- 25 °C
Additional information
TDI is rapidly hydrolysed in aqueous solution, with a half-life of under one minute (Yakabe et al., 1999). The product of hydrolysis of the isocyanate group is an amine, which itself reacts with another isocyanate group to yield a urea. This reaction of an amine with isocyanate is considerably faster than the reaction of water with the isocyanate (Yakabe et al, 1999). With TDI, a diisocyanate, this reaction leads to polyureas, which are inert, insoluble solids.
However TDI is hydrophobic and poorly soluble in water (West et al., 2008), and such fast reaction is only achieved by vigorous agitation of the mixture. When the denser diisocyanate is less well dispersed into water, the reaction is heterogeneous (at the interface) and is slower. The reaction leads to the formation of a solid crust of polyureas encasing unreacted material. This crust restricts ingress of water and egress of amine, and thereby slows hydrolysis even further and enhances the amine reaction with isocyanate, leading to an even higher yield of polyureas.
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