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Diss Factsheets
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EC number: 204-402-9 | CAS number: 120-51-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1983
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Principles of method if other than guideline:
- The method is based on the measurement of the substance concentration in the saturated vapor phase (headspace) which stays in equilibrium with the condensed phase. During the procedure the total amount of substance being present in a defined volume of vapor is collected on an adsorbent and quantified either by gravimetry or, after desorption from the carrier, by chromatography.
A solution of about 100 mg of the substance in 2 ml of pentane is distributed in a 1 L-headspace vesselin such a way that the wall and floor are well wetted. After evaporation of the solvent the vessel is closed by putting on the hood and the
Carbon filter. The apparatus is set in a water bath at 25 °C and allowed to equilibrate for 2 hours. The two Porapak filter inside the headspace vessel are then connected in series at a height of approx. 2 cm above the bottom of the vessel and the headspace
withdrawal using a 100 ml suction device (measured volume 78 ml) at a suction speed of 5 ml / min engaged. After the suction process has ended, additional 5 min are waited to complete pressure equilibration.
To ensure that the substance has been held beack in the front filter quantitatively the downstream filter is desorbed with 70 μl of hexane and the desorbate is checked for the absence of the substance by gas chromatography on a 2 m long column (Carbowax 20M). The front filter containing the amount of substance quantitatively is now slowly (2-3min) desorbed with 70 μl of hexane into a weighed mixing vessel and the volume of the desorbate is determined gravimetrically.
Before characterizing the desorbate by gas chromatography the sample is homgenized by at least 10 times aspiration and expulsion with a syringe.
After having 2 to 3 very well comparable chromatograms (i.e. the sample is homogeneous) a standard solution containing the substance is made in such a way that its peak area or Peak height may derive not more than +/- 20% of the specified value of the sample. Finally, the complete desorption of the substance from the filter by desorbing it again with 70µL Hexane and by gas chromatographic analysis of the post-extract checked.
Samples are prepared in triplicate and 2 to 3 gas chromatograms are recorded.
Amount of substance is determined by comparing the mean peak heights measured with those of an external standard of known concentration. - GLP compliance:
- not specified
- Type of method:
- gas saturation method
- Key result
- Test no.:
- #1
- Temp.:
- 25 °C
- Vapour pressure:
- 0.003 Pa
- Remarks on result:
- other: headspace method
- Test no.:
- #2
- Temp.:
- 25 °C
- Vapour pressure:
- 0.004 Pa
- Remarks on result:
- other: Knudsen-method
- Test no.:
- #1
- Temp.:
- ca. 25 °C
- Vapour pressure:
- ca. 0 Torr
- Conclusions:
- The vapour pressure of benzyl benzoate determined by headspace gas saturation method is 0.00305 Pa at 25 °C.
- Executive summary:
The vapour pressure of benzyl benzoate determined by headspace gas saturation method is 0.00305 Pa (equivalent to 0.000229 Torr (mmHg))
at 25 °C. The article references the vapour pressure determined by a Knudsen cell with 0.00404 Pa at 25 °C.
- Endpoint:
- vapour pressure
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Reason / purpose for cross-reference:
- other: input value used for calculation
- Reason / purpose for cross-reference:
- other: input value for calculation
- Guideline:
- other: ECHA Guidance Document R.16
- Version / remarks:
- Version 3.0, February 2016
- GLP compliance:
- no
- Type of method:
- other: calculation
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 0.02 Pa
- Remarks on result:
- other: Temperature of water solubility used for estimation.
- Conclusions:
- The vapour pressure of benzyl benzoate was calculated using water solubility, HLC, and molecular weight to 0.0205 Pa.
- Executive summary:
The vapour pressure of benzyl benzoate was calculated using the experimentally determined water solubility of 15.3 mg/L at 20 °C, a HLC of 0.284 Pa*m3/mol (estimated by QSAR), and molecular weight of 212.25 g /mol to 0.0205 Pa at 20 °C (setting the estimation at the same temperature as the water solubility data used.
Referenceopen allclose all
By using the measured water solubility of 15.3 mg/L, the molecular weight of 212.25 g/mol and the estimated Henry's Law Constant of 0 2.84E-01 Pa*m3/mol, the vapour pressure can be calculated as 0.0205 Pa.
Description of key information
The vapour pressure of benzyl benzoate determined in a study by Etzweiler et al. is 0.0305 Pa at 25 °C. The article references the vapour pressure determined by a Knudsen cell with 0.0404 Pa at 25 °C.
Key value for chemical safety assessment
- Vapour pressure:
- 0.03 Pa
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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