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Diss Factsheets
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EC number: 204-402-9 | CAS number: 120-51-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Study period:
- 13/11/2012
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- The bioconcentration factor of benzyl benzoate in fish was estimated from the log Kow using BCFBAF v3.01. An experimental log Kow was available for benzyl benzoate in the program.
- Principles of method if other than guideline:
- The bioconcentration factor of benzyl benzoate in fish was estimated from the log Kow using BCFBAF v3.01. An experimental log Kow was available for benzyl benzoate in the program.
- GLP compliance:
- no
- Details on sampling:
- Not applicable
- Details on preparation of test solutions, spiked fish food or sediment:
- Not applicable
- Test organisms (species):
- no data
- Hardness:
- Estimation by QSAR
- Test temperature:
- Estimation by QSAR
- pH:
- Estimation by QSAR
- Dissolved oxygen:
- Estimation by QSAR
- TOC:
- Estimation by QSAR
- Salinity:
- Estimation by QSAR
- Details on test conditions:
- Estimation by QSAR
- Nominal and measured concentrations:
- Estimation by QSAR
- Details on estimation of bioconcentration:
- The bioconcentration factor was estimated using BCFBAF v3.01. The equation used to make the BCF estimate was:
log BCF= 0.6598 log Kow - 0.333 + correction
In this case the experimental log Kow was 3.97 and no correction factor was applicable. - Type:
- BCF
- Value:
- 193.4 L/kg
- Basis:
- whole body w.w.
- Remarks on result:
- other: QSAR estimate
- Details on kinetic parameters:
- Not applicable
- Metabolites:
- Not applicable
- Results with reference substance (positive control):
- Not applicable
- Details on results:
- The estimated log BCF was 2.286 (BCF= 193.4 L/kg wet-wt)
- Conclusions:
- Based on a QSAR carried out using an experimental log Kow, the log BCF of benzyl benzoate in fish was estimated to be 2.286 (BCF= 193.4 Lkg wet-wt).
- Executive summary:
The bioconcentration factor of benzyl benzoate was estimated by QSAR. the QSAR was carried out using BCFBAF v3.01 and an experimental log Kow value of 3.97. The following equation was used:
log BCF= 0.6598 log Kow - 0.333 + correction
No correction factor was used in this case. The log BCF was estimated to be 2.286 (BCF = 193.4 L/kg wet-wt).
Due to the readily biodegradable nature of benzyl benzoate, exposure to the aquatic environment is likely to be limited. The readily biodegradable nature of the substance will also mean that the BCF will be lower than that estimated from the log Kow of the substance, as it expected to be metabolised by aquatic microorganisms.
Reference
No further information
Description of key information
The BCF of benzyl benzoate was estimated to be 193.4 L/kg using BCFBAF v3.01 (log BCF= 2.286).
Key value for chemical safety assessment
- BCF (aquatic species):
- 193.4 L/kg ww
Additional information
The bioconcentration factor of benzyl benzoate was estimated by QSAR. the QSAR was carried out using BCFBAF v3.01 and an experimental log Kow value of 3.97. The following equation was used:
log BCF= 0.6598 log Kow - 0.333 + correction
No correction factor was used in this case. The log BCF was estimated to be 2.286 (BCF = 193.4 L/kg wet-wt).
Due to the readily biodegradable nature of benzyl benzoate, exposure to the aquatic environment is likely to be limited. The readily biodegradable nature of the substance will also mean that the BCF will be lower than that estimated from the log Kow of the substance, as it expected to be metabolised by aquatic microorganisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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