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EC number: 262-104-4 | CAS number: 60207-90-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 07 Mar 1990 to 04 Apr 1990
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Version / remarks:
- 12. May 1981
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- - Inoculum: Bacteria collected from sludge of the sewage treatment plant of CH-4153 Reinach on 06/03/90. The was carried out the method described in the guideline.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 10.9 mg/L
- Based on:
- test mat.
- Initial conc.:
- 20.7 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST DESIGN
- Test concentrations: 1200 mL of the mineral solution with the inoculum were aerated for 24 hours in the test vessel. In 300 ml, mineral solution 15 mL Polyoxyethylene-Sorbitan-mono oleate (solution of 30 mg in 100 mL bidist. water) and 16.4 rsp. 31.1 mg of test substance were added and homogenized. This solution was given to the test vessel which was immediately connected to the CO2 traps.
- Blank: Water as specified in the guideline containing 15 mL of the Polyoxy-ethylene-Sorbitan monooleate solution.
- Vessels: 2L flasks (dark brown glass) equipped with gas inlet and magnetic stirrer.
- Water: The test medium was prepared according to the method described in the guideline.
- Temperature: 20 - 24 °C
- Air: ~ 25 mL/mon purified from carbon dioxide. - Reference substance:
- aniline
- Test performance:
- Theoretical carbon dioxide evolution per concentration:
- Test substance: 10.9 mg/L resulted in 28.82 mg CO2/1.5L
- Test substance: 20.7 mg/Lresulted in 54.65 mg CO2/1.5L
(This calculation is based on the chemical formula in consideration of the purity of 91.1%.) - Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 0
- Sampling time:
- 28 d
- Remarks on result:
- other: The biodegradation was calculated for 10.9 mg test substance/L
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 3
- Sampling time:
- 28 d
- Remarks on result:
- other: The biodegradation was calculated for 20.7 mg test substance/L
- Details on results:
- No biodegradation was observed throughout the test
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The substance is not biodegradable in this test.
- Executive summary:
The biodegradability of the test substance was investigated in a CO2 evolution test using domestic aerobic activated sewage sludge in accordance with OECD TG 301 B and in compliace with GLP criteria. The test substance concentrations were 10.9 mg/L and 20.7 mg/L in the test and the blank control of the emulsifier and the reference substance were included in the test. The results showed a maximum of 3% degradation (based on theoretical carbon dioxide) within 28 days. During the study 0 % biodegradation occurred at the lower concentration and 3 % in the higher. Based on these findings, it is concluded that the test substance is not readily biodegradable.
Reference
Table. CO2 evolution and Biodegradation for the blank, reference and substance.
|
CO2 evolution measured |
Biodegradation |
||||||||||
|
Blank |
Reference |
Reference |
|||||||||
|
1 |
2 |
mean |
1 |
2 |
1 |
2 |
mean |
||||
day |
[mg] |
[mg] |
[mg] |
[mg] |
[mg] |
% |
% |
% |
||||
2 |
4.3 |
4.9 |
4.6 |
4.2 |
4.8 |
0 |
0 |
0 |
||||
5 |
7.9 |
8.9 |
8.4 |
33.0 |
64.3 |
29 |
66 |
47 |
||||
9 |
10.4 |
11.9 |
11.1 |
75.0 |
81.2 |
75 |
82 |
79 |
||||
12 |
11.5 |
13.0 |
12.2 |
83.3 |
88.1 |
84 |
89 |
86 |
||||
16 |
13.1 |
14.4 |
13.8 |
90.5 |
93.7 |
90 |
94 |
92 |
||||
19 |
13.5 |
15.1 |
14.3 |
91.8 |
94.7 |
91 |
95 |
93 |
||||
23 |
14.4 |
15.6 |
15.0 |
94.0 |
100.1 |
93 |
100 |
96 |
||||
27 |
15.4 |
16.5 |
15.9 |
94.9 |
100.3 |
93 |
99 |
96 |
||||
28 |
15.9 |
16.5 |
16.2 |
98.3 |
100.9 |
97 |
100 |
98 |
||||
Substance |
CO2 evolution measured |
Biodegradation |
||||||||||
10.9 mg/L |
20.7 mg/L |
10.9 mg/L |
20.7 mg/L |
|||||||||
Day |
[mg] |
[mg] |
% |
% |
||||||||
2 |
4.3 |
4.0 |
-1 |
-1 |
||||||||
5 |
7.6 |
8.5 |
-3 |
0 |
||||||||
9 |
10.2 |
12.4 |
-3 |
2 |
||||||||
12 |
11.8 |
14.0 |
-2 |
3 |
||||||||
16 |
13.9 |
15.6 |
0 |
3 |
||||||||
19 |
14.3 |
16.1 |
0 |
3 |
||||||||
23 |
15.1 |
17.2 |
0 |
4 |
||||||||
27 |
15.6 |
17.8 |
-1 |
3 |
||||||||
28 |
15.9 |
18.0 |
-1 |
3 |
The negative degradation values are within the variation of the method.
Description of key information
The substance is not biodegradable under the test conditions, OECD TG 301B, Bader 1990.
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
- Type of water:
- freshwater
Additional information
There is one OECD TG 301 B followed and GLP complied study available for this endpoint. The ready biodegradability of the substance was investigated in a CO2 evolution test using domestic aerobic activated sewage sludge. The test substance concentrations were 10.9 mg/L and 20.7 mg/L. The results showed a maximum of 3% degradation (based on theoretical carbon dioxide) within 28 days. Therefore, it is concluded that the test substance is not readily biodegradable (Bader 1990, Reliability 1).
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