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Diss Factsheets
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EC number: 264-150-0 | CAS number: 63449-39-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu./o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_environmental-fate-and-pathways.png)
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation: aquatic / sediment
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Study period:
- 2009
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Accepted estimation technique.
Data source
Reference
- Reference Type:
- publication
- Title:
- Environmental Risk Evaluation Report: Long-Chain Chlorinated Paraffins.
- Author:
- UK Environment Agency
- Year:
- 2 009
- Bibliographic source:
- UK Environment Agency
- Report date:
- 2009
Materials and methods
- Principles of method if other than guideline:
- Estimate, TGD Section 3.8.3.2. According to the TGD, the bioconcentration factor (BCF) for fish can be estimated from the following equation.
log BCF = -0.20×(log Kow)2 + 2.74×log Kow - 4.72
where log Kow = 9.7
The equation applies to substances with log Kow >6 and molecular weights <700g/mole. - GLP compliance:
- no
Test material
- Reference substance name:
- Paraffin waxes and Hydrocarbon waxes, chloro
- EC Number:
- 264-150-0
- EC Name:
- Paraffin waxes and Hydrocarbon waxes, chloro
- Cas Number:
- 63449-39-8
- Molecular formula:
- C18H33Cl5 C18H30Cl8 C20H36Cl6 C20H33Cl9 C25H45Cl7 C25H42Cl10 C25H29C23 C30H53Cl9 C30H49Cl13 C30H35Cl27
- IUPAC Name:
- Paraffin waxes and Hydrocarbon waxes (C18 and longer), chloro
Constituent 1
- Radiolabelling:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- other: model results
Study design
- Route of exposure:
- other: model results
- Test type:
- other: model results
Results and discussion
Bioaccumulation factoropen allclose all
- Type:
- BCF
- Value:
- 1 096 L/kg
- Basis:
- other: model result
- Calculation basis:
- steady state
- Remarks on result:
- other: C18-C20 liquid
- Type:
- BCF
- Value:
- 192 L/kg
- Basis:
- other: model result
- Calculation basis:
- steady state
- Remarks on result:
- other: C20-C30 liquid LCCP
- Type:
- BCF
- Value:
- < 1 L/kg
- Basis:
- other: model result
- Calculation basis:
- steady state
- Remarks on result:
- other: C20-C30 solid
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- C18‑20liquid LCCP BCF = 1,096 L/kg
C20-30liquid LCCP BCF = 192 L/kg
C20-30solid LCCP BCF <1 L/kg - Executive summary:
The potential for uptake and accumulation of the substance by fish and other aquatic and terrestrial organisms is uncertain, but appears to decrease with increasing carbon chain length and increasing degree of chlorination. The model estimated BCFs in fish for the LCCP are as follows (method taken from the EU Technical Guidance Document parabolic equation, application for substances with log Kow >6 and molecular weight < 700 g/mol: log BCF = -0.2 x(log Kow)2+ (2.74 x log Kow – 4.72); (Veith et al, 1979):
C18‑20liquid LCCP BCF = 1,096 L/kg
C20-30liquid LCCP BCF = 192 L/kg
C20-30solid LCCP BCF <1 L/kg
There is evidence from feeding studies that LCCPs can be taken up via the diet, but in all cases the concentrations reached in the animals were less than those in the diet. This indicates that although uptake of the substance can occur via the food, the levels should not increase through the food chain (UK EA 2009).
Based on the estimates of BCF and taking the known accumulation properties of structurally similar substances (SCCPs and MCCPs) into account, the BCF for LCCPs is considered to be <2,000 L/kg (UK EA, 2009). Thus it is concluded that LCCPs are unlikely to meet the B or vB (very bioaccumulative) EU criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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