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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 202-486-1 | CAS number: 96-18-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The data are from an official Japanese data base on experimental data for biodegradation that is well recognised by authorities. The study was performed under standard conditions, but no details on the test are available.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 305 (Bioconcentration: Flow-through Fish Test)
- Deviations:
- not specified
- GLP compliance:
- no
- Radiolabelling:
- no
- Details on sampling:
- No data
- Details on preparation of test solutions, spiked fish food or sediment:
- A dispersant (HCO-40) was used to prepare the test solutions. No additional data available.
- Test organisms (species):
- Cyprinus carpio
- Details on test organisms:
- Average lipid content was 5.1 %, no additional data on fish available
- Route of exposure:
- aqueous
- Test type:
- flow-through
- Water / sediment media type:
- natural water: freshwater
- Total exposure / uptake duration:
- 6 wk
- Hardness:
- No data
- Test temperature:
- No data
- pH:
- No data
- Dissolved oxygen:
- No data
- TOC:
- No data
- Salinity:
- No data
- Details on test conditions:
- No data
- Nominal and measured concentrations:
- Nominal concentrations were 0.02 and 0.2 %
- Reference substance (positive control):
- not specified
- Details on estimation of bioconcentration:
- No data
- Lipid content:
- 5.1 %
- Time point:
- end of exposure
- Type:
- BCF
- Value:
- >= 5.3 - <= 13 dimensionless
- Basis:
- not specified
- Remarks on result:
- other: Conc.in environment / dose:0.02 %
- Type:
- BCF
- Value:
- >= 5.4 - <= 12 dimensionless
- Basis:
- not specified
- Remarks on result:
- other: Conc.in environment / dose:0.2 %
- Details on kinetic parameters:
- No data
- Metabolites:
- No data
- Results with reference substance (positive control):
- No data
- Details on results:
- No data
- Reported statistics:
- No data
- Validity criteria fulfilled:
- yes
- Conclusions:
- The bioconcentration factor of 1,2,3-trichloropropane in fish ranged from 5.3 to 13.
- Executive summary:
The bioconcentration factor of 1,2,3-trichloropropane was tested in accordance with OECD Guideline 305 over six weeks in a continuous flow-through system using carp (Cyprinus carpio). Two levels of 0.02 and 0.2 % were tested. The test solutions were prepared with the dispersant HCO-40. The fish had on average a lipid content of 5.1 %. The bioconcentration factors found at the low dose ranged from 5.3 to 13, and corresponding factors at the high dose ranged from 5.4 to 12.
Reference
Description of key information
Key value for chemical safety assessment
- BCF (aquatic species):
- 13 dimensionless
Additional information
The bioconcentration factor of TCP was tested in accordance with OECD Guideline 305 over six weeks in a continuous flow-through system using carp (Cyprinus carpio) (MITI 1992). Two levels of 0.02 and 0.2 % were tested. The test solutions were prepared with the dispersant HCO-40. The fish had on average a lipid content of 5.1 %. The bioconcentration factors found at the low dose ranged from 5.3 to 13, and corresponding factors at the high dose ranged from 5.4 to 12.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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