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Diss Factsheets
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EC number: 215-553-5 | CAS number: 1330-86-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu./o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.865 mg/kg soil dw
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
According to Article 13 of Regulation (EC) No. 1907/2006 "General Requirements for Generation of Information on Intrinsic Properties of substances", Information on intrinsic properties of substances may be generated by means other than tests e.g. from information from structurally related substances (grouping or read-across), provided that conditions set out in Annex XI are met.
Annex XI, "General rules for adaptation of this standard testing regime set out in Annexes VII to X” states that “substances whose physicochemical, toxicological and ecotoxicological properties are likely to be similar or follow a regular pattern as a result of structural similarity may be considered as a group, or ‘category’ of substances. This avoids the need to test every substance for every endpoint”.
Since the group concept is applied to the category members of the PFAE linear, data will be generated from a representative category member to avoid unnecessary animal testing. Additionally, once the group concept is applied, substances will be classified and labelled on this basis.
Conclusion on classification
Classification related key information
Log Kow: 8.2 (KOWWIN v1.68)
Water solubility: < 0.05 mg/L (EC Guideline A.6)
Biodegradation: 70 % in 28 days (OECD 301F)
BCF: 5 L/kg (BCFBAF v3.01; Arnot-Gobas estimate)
Aquatic acute toxicity:
For fish: LC50 (96h) no toxic effects up to the limit of water solubility (< 0.05 mg/L) for fish (OECD 203), read across
For algae: EC50 (72h) no toxic effects up to the limit of water solubility (< 0.05 mg/L) for algae (OECD 201), read across
For crustacea: EC50 (48h) no toxic effects up to the limit of water solubility (< 0.05 mg/L) for D. magna (OECD 202), read across
Aquatic chronic toxicity:
For fish: no data
For algae: NOEC (72h) no toxic effects up to the limit of water solubility (< 0.05 mg/L) for algae (OECD 201), read across
For crustacean: NOErC (21d) no toxic effects up to the limit of water solubility (< 0.05 mg/L) for D. magna (OECD 211), read across
Non-Classification justification according to CLP
Based on read across, the acute aquatic toxicity L(E)C50 is above the limit of water solubility for fish, algae and aquatic invertebrates. Diisooctyl adipate (CAS 1330-86-5) does not need to be classified and labeled as acute aquatic hazard according to the 2nd ATP of the Regulation (EC) No.1272/2008 (CLP).
Diisooctyl adipate (CAS 1330-86-5) is considered to be rapidly degradable. Valid chronic toxicity data are available to invertebrates and algae (read across) – the NOEC is above the limit of water solubility for Daphnia magna. Therefore, Diisooctyl adipate (CAS 1330-86-5) does not need to be classified and labeled as long-term aquatic hazard according to the 2nd ATP of the Regulation (EC) No.1272/2008 (CLP).
M-factor for chronic aquatic toxicity: -
Non-Classification justification according to DSD
Based on the data above, Diisooctyl adipate (CAS 1330-86-5) is rapidly degradable and is considered to have a low potential for accumulation. The acute aquatic toxicity L(E)C50 is above the limit of water solubility in water for fish, algae and daphnia (based on read across). Therefore, Diisooctyl adipate (CAS 1330-86-5) does not need to be classified and labeled as environmental hazard according to Directive 67/548/EEC.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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