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Diss Factsheets
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EC number: 272-695-0 | CAS number: 68909-18-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.002 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.002 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 1.17 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.295 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.295 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.239 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
PNECwater
The lowest endpoint is for algae (EbC500.16 mg.L / ErC500.47 mg/L). Current guidance suggests the EC50for growth rate is used for risk assessment purposes in preference to the EC50for biomass.
No long-term aquatic endpoints are available.
For freshwater, an assessment factor (AF) of 1000 is applied for frequent/constant release:
PNECwater= 0.47 / 1000 = 0.00047 mg/L
For intermittent release, an assessment factor AF of 100 may be applied.
PNECwater, intermittent= 0.47 / 100 = 0.0047 mg/L
For marine water, an AF of 10000 is to be applied to reflect the greater diversity of taxa (producing a broader distribution of species sensitivity) in seawater.
PNECmarine water= 0.47 / 10000 = 0.000047 mg/L
PNECmicroorganisms
The activated sludge respiration inhibition test was performed according to OECD guideline 209 (Activated Sludge, Respiration Inhibition Test).
The following information is taken into account for effects on aquatic micro-organisms for the derivation of PNEC:
No notable inhibition was observed at the 1.9 or 6.1 mg/L nominal test concentrations (equivalent to 1.4, 4.8 mg/L active ingredient), however 8%, 40% and 61% inhibition was observed at nominal test concentrations of 19.5, 62.5 and 200.0 mg/L (equivalent to 14.7, 46.9 and 150.0 mg/L active ingredient), respectively.
Based on Probit analysis, the EC10, EC20 and EC50 were 18, 34 and 117 mg/L MK92K (equivalent to 13.6, 25.8 and 88.0 mg/L active ingredient), respectively. The EC80 could not be reliably determined but can be said to be greater than the highest test concentration, 200 mg/L MK92K (equivalent to >150 mg/L active ingredient). The NOEC is considered to be 6.1 mg/L MK92K (equivalent to 4.6 mg/L active ingredient).
The guideline validity criteria relating to the reference substance response and the variation between the blank control cultures were met. The results of this study are therefore considered valid. Using an assessment factor of 10 results in a PNEC of 0.61 mg/L
Exposure to terrestrial organisms is not expected on the basis of the use pattern of the substance.
Conclusion on classification
Based on the data available, MK92K is classified under Directive 67/548/EEC as (R50/53) Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment and under the CLP Regulation ad Aquatic Acute 1 (Hazard statement: H400: Very toxic to aquatic life.)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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