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Diss Factsheets
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EC number: 247-094-1 | CAS number: 25550-51-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu./o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Endpoint summary
Administrative data
Description of key information
Additional information
No data was available for MHHPA. Instead a read across approach was used, assessing data of 4- MHHPA, as these substance was considered to show similar ecotoxicological properties.
Acute immobilisation to Daphnia magna, algal growth inhibition to unicellular freshwater green alga and acute toxicity to fish have been investigated. In Daphnia and fish no effects were observed at a concentration of 100 mg/L. In algae, 4 –MHHPA was found to inhibit the growth after 72 hours exposure, EC50-values with 95 % confidence intervals for inhibition of specific growth rate (ErC50) and yield (EyC50) being 135 (127 – 143) mg/L and 81.3 (72.7 – 89.8) mg/L, respectively. In accordance with ECHA guidance on information requirements and chemical safety assessment, Chapter R.7b: Endpoint specific guidance, the ErC50 endpoint is used in DNEL derivation. This is because use of values based on biomass cannot be applied to an analysis of results from a system in exponential growth without logarithmic transformation.
Toxicity to microorganisms has been investigated in an activated sludge respiration inhibition test according to OECD test methods. 4 –MHHPA caused a concentration related inhibition ranging from 14% at 58 mg/L to 99% at 1000 mg/L. The EC50 was 219 (189 – 248) mg/L with concentrations of 95.3 mg/L and below causing less that 20% inhibition and regarded as not toxic to microorganisms of a municipal sewage treatment plant. EC10, estimated from reported EC20, EC50 and EC80 values, was approximately 70 mg/L. Effects or pH on inhibition were examined and found to be the major factor in determining effects, a concentration of 1000 mg/L causing <20% inhibition when pH was adjusted back to neutral.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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