Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-886-1 | CAS number: 128-44-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu./o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_manufacture-use-and-exposure.png)
Article service life
Documentsopen allclose all
Service life
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
- Article used by:
- workers
- Article category (AC):
- AC 0: Other: Food products
Contributing activity / technique for the environment
- Name of activity / technique:
- ERC12a: Processing of articles at industrial sites with low release
- Environmental release category (ERC):
- ERC12a: Processing of articles at industrial sites with low release
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 4: Chemical production where opportunity for exposure arises
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- PROC 5: Mixing or blending in batch processes
- Process category (PROC):
- PROC 5: Mixing or blending in batch processes
- Name of activity / technique:
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- PROC 13: Treatment of articles by dipping and pouring
- Process category (PROC):
- PROC 13: Treatment of articles by dipping and pouring
- Name of activity / technique:
- PROC 14: Tabletting, compression, extrusion, pelletisation, granulation
- Process category (PROC):
- PROC 14: Tabletting, compression, extrusion, pelletisation, granulation
- Related assessment:
- use not assessed
Service life
- Article used by:
- workers
- consumers
- Article category (AC):
- AC 0: Other: oral care products
Contributing activity / technique for the environment
- Name of activity / technique:
- ERC10a: Widespread use of articles with low release (outdoor)
- Environmental release category (ERC):
- ERC10a: Widespread use of articles with low release (outdoor)
Contributing activity / technique for consumers
- Name of activity / technique:
- oral care products
- Article category (AC):
- AC 0: Other: oral care products
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 4: Chemical production where opportunity for exposure arises
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- PROC 5: Mixing or blending in batch processes
- Process category (PROC):
- PROC 5: Mixing or blending in batch processes
- Name of activity / technique:
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- PROC 13: Treatment of articles by dipping and pouring
- Process category (PROC):
- PROC 13: Treatment of articles by dipping and pouring
- Name of activity / technique:
- PROC 19: Hand-mixing with intimate contact and only PPE available.
- Process category (PROC):
- PROC 19: Hand-mixing with intimate contact and only PPE available.
Service life
- Article used by:
- workers
- Article category (AC):
- AC 0: Other: laboratory chemicals
Contributing activity / technique for the environment
- Name of activity / technique:
- ERC10a: Widespread use of articles with low release (outdoor)
- Environmental release category (ERC):
- ERC10a: Widespread use of articles with low release (outdoor)
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- PROC 7: Industrial spraying
- Process category (PROC):
- PROC 7: Industrial spraying
- Name of activity / technique:
- PROC 10: Roller application or brushing
- Process category (PROC):
- PROC 10: Roller application or brushing
- Name of activity / technique:
- PROC 13: Treatment of articles by dipping and pouring
- Process category (PROC):
- PROC 13: Treatment of articles by dipping and pouring
- Name of activity / technique:
- PROC 15: Use as laboratory reagent
- Process category (PROC):
- PROC 15: Use as laboratory reagent
Service life
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
- Article used by:
- workers
- consumers
- Article category (AC):
- AC 0: Other: oral care products
Contributing activity / technique for the environment
- Name of activity / technique:
- ERC10a: Widespread use of articles with low release (outdoor)
- Environmental release category (ERC):
- ERC10a: Widespread use of articles with low release (outdoor)
Contributing activity / technique for consumers
- Name of activity / technique:
- oral care products
- Article category (AC):
- AC 0: Other: oral care products
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 4: Chemical production where opportunity for exposure arises
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- PROC 5: Mixing or blending in batch processes
- Process category (PROC):
- PROC 5: Mixing or blending in batch processes
- Name of activity / technique:
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- PROC 13: Treatment of articles by dipping and pouring
- Process category (PROC):
- PROC 13: Treatment of articles by dipping and pouring
- Name of activity / technique:
- PROC 19: Hand-mixing with intimate contact and only PPE available.
- Process category (PROC):
- PROC 19: Hand-mixing with intimate contact and only PPE available.
- Related assessment:
- use not assessed
Service life
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
- Article used by:
- workers
- consumers
- Article category (AC):
- AC 0: Other: pharmaceutical products
Contributing activity / technique for the environment
- Name of activity / technique:
- ERC10a: Widespread use of articles with low release (outdoor)
- Environmental release category (ERC):
- ERC10a: Widespread use of articles with low release (outdoor)
Contributing activity / technique for consumers
- Name of activity / technique:
- pharmaceutical products
- Article category (AC):
- AC 0: Other: pharmaceutical products
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 4: Chemical production where opportunity for exposure arises
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- PROC 5: Mixing or blending in batch processes
- Process category (PROC):
- PROC 5: Mixing or blending in batch processes
- Name of activity / technique:
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- PROC 14: Tabletting, compression, extrusion, pelletisation, granulation
- Process category (PROC):
- PROC 14: Tabletting, compression, extrusion, pelletisation, granulation
- Name of activity / technique:
- PROC 19: Hand-mixing with intimate contact and only PPE available.
- Process category (PROC):
- PROC 19: Hand-mixing with intimate contact and only PPE available.
- Related assessment:
- use not assessed
Service life
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
- Article used by:
- workers
- Article category (AC):
- AC 0: Other: laboratory chemicals
Contributing activity / technique for the environment
- Name of activity / technique:
- ERC10a: Widespread use of articles with low release (outdoor)
- Environmental release category (ERC):
- ERC10a: Widespread use of articles with low release (outdoor)
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- PROC 7: Industrial spraying
- Process category (PROC):
- PROC 7: Industrial spraying
- Name of activity / technique:
- PROC 10: Roller application or brushing
- Process category (PROC):
- PROC 10: Roller application or brushing
- Name of activity / technique:
- PROC 13: Treatment of articles by dipping and pouring
- Process category (PROC):
- PROC 13: Treatment of articles by dipping and pouring
- Name of activity / technique:
- PROC 15: Use as laboratory reagent
- Process category (PROC):
- PROC 15: Use as laboratory reagent
- Related assessment:
- use not assessed
Service life
- Article used by:
- workers
- Article category (AC):
- AC 0: Other: Food products
Contributing activity / technique for the environment
- Name of activity / technique:
- ERC12a: Processing of articles at industrial sites with low release
- Environmental release category (ERC):
- ERC12a: Processing of articles at industrial sites with low release
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 4: Chemical production where opportunity for exposure arises
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- PROC 5: Mixing or blending in batch processes
- Process category (PROC):
- PROC 5: Mixing or blending in batch processes
- Name of activity / technique:
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- PROC 13: Treatment of articles by dipping and pouring
- Process category (PROC):
- PROC 13: Treatment of articles by dipping and pouring
- Name of activity / technique:
- PROC 14: Tabletting, compression, extrusion, pelletisation, granulation
- Process category (PROC):
- PROC 14: Tabletting, compression, extrusion, pelletisation, granulation
Service life
- Article used by:
- workers
- Article category (AC):
- AC 7: Metal articles
Contributing activity / technique for the environment
- Name of activity / technique:
- ERC10a: Widespread use of articles with low release (outdoor)
- Environmental release category (ERC):
- ERC10a: Widespread use of articles with low release (outdoor)
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- PROC 7: Industrial spraying
- Process category (PROC):
- PROC 7: Industrial spraying
- Name of activity / technique:
- PROC 10: Roller application or brushing
- Process category (PROC):
- PROC 10: Roller application or brushing
- Name of activity / technique:
- PROC 13: Treatment of articles by dipping and pouring
- Process category (PROC):
- PROC 13: Treatment of articles by dipping and pouring
- Name of activity / technique:
- PROC 15: Use as laboratory reagent
- Process category (PROC):
- PROC 15: Use as laboratory reagent
Service life
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
- Article used by:
- workers
- Article category (AC):
- AC 7: Metal articles
Contributing activity / technique for the environment
- Name of activity / technique:
- ERC10a: Widespread use of articles with low release (outdoor)
- Environmental release category (ERC):
- ERC10a: Widespread use of articles with low release (outdoor)
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- PROC 7: Industrial spraying
- Process category (PROC):
- PROC 7: Industrial spraying
- Name of activity / technique:
- PROC 10: Roller application or brushing
- Process category (PROC):
- PROC 10: Roller application or brushing
- Name of activity / technique:
- PROC 13: Treatment of articles by dipping and pouring
- Process category (PROC):
- PROC 13: Treatment of articles by dipping and pouring
- Name of activity / technique:
- PROC 15: Use as laboratory reagent
- Process category (PROC):
- PROC 15: Use as laboratory reagent
- Related assessment:
- use not assessed
Service life
- Article used by:
- workers
- consumers
- Article category (AC):
- AC 0: Other: pharmaceutical products
Contributing activity / technique for the environment
- Name of activity / technique:
- ERC10a: Widespread use of articles with low release (outdoor)
- Environmental release category (ERC):
- ERC10a: Widespread use of articles with low release (outdoor)
Contributing activity / technique for consumers
- Name of activity / technique:
- pharmaceutical products
- Article category (AC):
- AC 0: Other: pharmaceutical products
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- PROC 4: Chemical production where opportunity for exposure arises
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- PROC 5: Mixing or blending in batch processes
- Process category (PROC):
- PROC 5: Mixing or blending in batch processes
- Name of activity / technique:
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- PROC 14: Tabletting, compression, extrusion, pelletisation, granulation
- Process category (PROC):
- PROC 14: Tabletting, compression, extrusion, pelletisation, granulation
- Name of activity / technique:
- PROC 19: Hand-mixing with intimate contact and only PPE available.
- Process category (PROC):
- PROC 19: Hand-mixing with intimate contact and only PPE available.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)