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Diss Factsheets
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EC number: 233-215-5 | CAS number: 10081-67-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
The substance is not considered to be persistent within the environment.
Additional information
- Soil simulation testing (Annex IX, Section 9.2.1.3.; test method: Aerobic and anaerobic transformation in soil, EU C.23./OECD TG 307) at a temperature of 12 °C with the registered substance;
- Sediment simulation testing (Annex IX, Section 9.2.1.4.; test method: Aerobic and anaerobic transformation in aquatic sediment systems, EU C.24./OECD TG 308) at a temperature of 12 °C with the registered substance
Ready biodegradation.
The biodegradability of the test substance was assessed using two different methods:
Method A - Carbon dioxide (CO2) evolution - Modified Sturm test
Method B - Closed bottle test (two-phase closed bottle test)
Based on the results of the biodegradability tests using the method of determination of evolved carbon dioxide(method A)and the closed bottle test (two-phase closed bottle test)(method B), the following biodegradability values were established for the test substance after 28 days:
Dt = 29% (method A)
DThOD = 5% (method B)
The test substance under the test conditions (method A) and (method B), cannot be considered to be readily biodegradable (D < 60%).
Results from simulation testing on degradation in soil;
In accordance with ECHA Decision number: CCH-D-2114494377-34-01/F, the following studies were conducted for environmental fate:
The results of this study are as follows:
The output values for the chosen model for each test system are presented in the table below.
Soil type | Model | r2 | χ2 (%) | DT90 at 12°C (days) | DT50 at 12°C (days) |
Soil I | SFO | 0.9288 | 13 | 88.4 | 26.6 |
Soil II | SFO | 0.8996 | 8.12 | 263 | 79.3 |
Soil III | HS | 0.9583 | 4.98 | 498 | 102 |
Soil IV | HS | 0.9886 | 3.45 | 158 | 88.4 |
[14C]4-(1-methyl-1-phenylethyl)-N-[4-(1-methyl-1-phenylethyl)phenyl]aniline disappeared over time in all soils, with DT50 values of 26.6, 79.3, 102 and 88.4 days in Soils I, II, III and IV respectively.
Almost no mineralisation occurred, with < 2% measured in all soils over 120 days.
10%, 12%, 14% and 4% of applied radioactivity remained in the soil residue for Soils I, II, III and IV respectively at Day 120 after all extractions had been carried out. ‘Harsh’ ASE extractions removed less than 2% of applied radioactivity. Therefore, these residues are not considered to be bioavailable and binding to soils was considered a pathway for disappearance.
(c) Results from simulation testing on degradation in sediment;
In accordance with ECHA Decision number: CCH-D-2114494377-34-01/F, the following studies were conducted for environmental fate:
The results of this study are as follows:
The output values for the chosen model for each test system are presented in the table below.
Test system | Compartment | Model | r2 | χ2 (%) | DT90 at 12°C (days) | DT50 at 12°C (days) |
HOC | Overlying water | SFO | 0.9967 | 7.36 | 11.1 | 3.35 |
Sediment extracts | HS | 0.9938 | 5.94 | 90.2 | 43.2 | |
Total system | HS | 0.9969 | 3.51 | 82.2 | 37.5 | |
LOC | Overlying water | SFO | 1.0000 | nd | 43.9 | 13.2 |
Sediment extracts | SFO | 0.6990 | 23.2 | 165 | 49.7 | |
Total system | SFO | 0.7792 | 20.1 | 135 | 40.6 |
nd: not determined
[14C]4-(1-methyl-1-phenylethyl)-N-[4-(1-methyl-1-phenylethyl)phenyl]aniline dissipated over time from the water phase to the sediment phase in both sediment types, with overlying water DT50 values of 3.35 and 13.2 days in the HOC and LOC test systems respectively. [14C]4-(1-methyl-1-phenylethyl)-N-[4-(1-methyl-1-phenylethyl)phenyl]aniline degraded more rapidly in the HOC sediment than the LOC sediment, with total system, reflected in the total system DT50 values of 37.5 and 40.6 days respectively.
Almost no mineralisation occurred, with <1% measured in both the HOC and LOC systems on Day 101.
8.8% and 7.6% of applied radioactivity remained in the sediment on Day 101 as bound radioactivity in the HOC and LOC test systems respectively after all extractions had been carried out. ASE extractions removed less than 10% of applied radioactivity. Therefore, these residues are not considered to be bioavailable and binding to sediments was considered a pathway for disappearance.
(d) Other information, such as information from field studies or monitoring studies, provided that its suitability and reliability can be reasonably demonstrated.
Assessment of the propensity of the substance to abiotically degrade is available and is as follows:
Method | Results |
according to guideline OECD Guideline 111 (Hydrolysis as a Function of pH) ; according to guideline EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH) ; according to guideline EPA OPPTS 835.2120 (Hydrolysis of Parent and Degradates as a Function of pH at 25°C)
| Half-life (DT50): t1/2 (pH 4): 53 d at 20°C; Type: (pseudo-)first order (= half-life) t1/2 (pH 4): 26 d at 25°C; Type: (pseudo-)first order (= half-life) t1/2 (pH 4): 25 h at 50°C; Type: (pseudo-)first order (= half-life) t1/2 (pH 4): 11 h at 60°C; Type: (pseudo-)first order (= half-life) t1/2 (pH 7): 25 d at 20°C; Type: (pseudo-)first order (= half-life) t1/2 (pH 7): 14 d at 25°C; Type: (pseudo-)first order (= half-life) t1/2 (pH 7): 24 h at 50°C; Type: (pseudo-)first order (= half-life) t1/2 (pH 7): 16 h at 60°C; Type: (pseudo-)first order (= half-life) t1/2 (pH 9): 18 d at 25°C; Type: (pseudo-)first order (= half-life) t1/2 (pH 9): 34 d at 20°C; Type: (pseudo-)first order (= half-life) Recovery (in %): Transformation products: not measured
|
The substance demonstrates a propensity towards degradation via abiotic routes.
Conclusion:
The substance is not considered to be persistent within the environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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