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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 205-355-7 | CAS number: 139-13-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
INHALATION
Move the exposed person to fresh air at once. Get medical attention if symptoms persist.
INGESTION
Wash out mouth with water, provided person is conscious. Get medical attention immediately.
SKIN CONTACT
Remove contaminated clothing and wash skin with soap and plenty of running water. Get medical attention if symptoms persist.
EYE CONTACT
Rinse immediately eye with plenty of low pressure water for at least 15 minutes.
Remove any contact lenses. Get medical attention immediately.
Fire-fighting measures
EXTINGUISHING MEDIA
To extinguish fire use water spray, dry powder, carbon dioxide, or foam.
SPECIAL FIRE FIGHTING PROCEDURES
Prevent run-off water from entering the sewer system.
UNUSUAL FIRE & EXPLOSION HAZARDS
None known.
SPECIFIC HAZARDS
By fire toxic gases may be formed (Cox, NOx).
PROTECTIVE MEASURES IN FIRE
Self contained breathing apparatus and full protective clothing.
Accidental release measures
PERSONAL PRECAUTIONS
See section on exposure controls/personal protection
ENVIRONMENTAL PRECAUTIONS
Take precautionary measures against discharges into the environment.
SPILL CLEAN UP METHODS
Collect spilled material without creating dust, then place into a suitable closed container for disposal as chemical waste.
Handling and storage
USAGE PRECAUTIONS
Avoid contact with eyes and skin.
Wash thoroughly after handling and before eating, drinking or smoking.
STORAGE PRECAUTIONS
To protect product quality, store in sealed container in a cool place and out of direct sunlight.
Transport information
Shippingopen allclose all
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
Shippingopen allclose all
Remarksopen allclose all
Shippingopen allclose all
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
EXPOSURE LIMITS
WHO (1993): international drink water guideline for nitrilotriacetic acid: 200 microgram/L
USE LIMITS
See below.
PNECs (see also section 12):
aqua-freshwater: 0.69 mg/L
aqua-marine water: 0.069 mg/L
aqua-intermittent: 6.9 mg/L
sewage treatment plant: 400 mg/L
soil 0.73 mg/kg dw
There are neither monitoring data for sediments nor toxicity tests with benthic organisms available. The NTA concentration can be modelled using the equilibrium partitioning method. A risk assessment for sediments will then lead to identical PEC/PNEC ratios like for the aquatic compartment. Because of the low partitioning coefficients, no accumulation in sediments is expected. Thus an assessment of this sub-compartment is not necessary.
DNELs:
The main derived long-term DNELs for systemic effects are:
Workers General population
Oral not relevant 0.11 mg/kg bw/day
Dermal 0.37 mg/kg bw/day 0.185 mg/kg bw/day
Inhalation 0.2 mg/m3/day 0.048 mg/m3/day
The CHESAR v2.3.0 model for this substance shows for indoor industrial activities taking more than 4 hours/day, with local exhaust ventilation present (and running), provided workers wear gloves with at least 90% protection (chemically resistant gloves conforming to EN374 with basic employee training) the following occupational exposures:
Inhalation dermal RCR RCR RCR
mg/m3 mg/kg/day inhalation dermal total
PROC4 0.035 0.069 0.175 0.185 0.36
Use in batch and other processes (synthesis) where opportunity for exposure arises
PROC5 0.035 0.137 0.175 0.37 0.545
Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact)
PROC8a 0.035 0.137 0.175 0.37 0.545
Transfer of chemicals from/to vessels/ large containers at non dedicated facilities
PROC8b 0.003 0.069 0.018 0.185 0.203
Transfer of chemicals from/to vessels/ large containers at dedicated facilities
PROC9 0.007 0.069 0.035 0.185 0.22
Transfer of substance or preparation into small containers (dedicated filling line, including weighing)
PROC15 0.007 0.003 0.035 0.009 0.044
Use as laboratory reagent
Note:
• Dustiness of the material has been set at low
• For workers a good general ventilation (3-5 air changes per hour) has been assumed; and an advanced occupational health and safety management system
• The substance is classified as an eye irritant category 2 with H319 (causes serious eye irritation). Wear approved safety goggles classified under EN 166:2001.
The CHESAR v2.3.0 model for this substance shows for indoor professional activities, with local exhaust ventilation present (and running), provided professional users wear gloves with at least 90% protection (chemically resistant gloves conforming to EN374 with basic employee training) the following occupational exposures:
PROC11 0.017 0.257 0.084 0.695 0.779
Non industrial spraying
PROC13 0.008 0.033 0.042 0.089 0.131
Treatment of articles by dipping and pouring
PROC19 0.001 0.283 0.007 0.765 0.772
Hand-mixing with intimate contact and only personal protection equipment available
Note:
• Dustiness of the material has been set at low
• For professionals a good general ventilation (3-5 air changes per hour) has been assumed; and a basic occupational health and safety management system
• For the professional uses (PROC 11, 13 and 19) it has been assumed that NTA is present in a preparation (mixture) at a concentration between 1 and 5%.
• PROC11 and PROC13 require a duration of activity of less than 4 hours per day; PROC19 requires less than 15 minutes.
• The substance is classified as an eye irritant category 2 with H319 (causes serious eye irritation). Wear approved safety goggles classified under EN 166:2001.
The ECETOC Consumer TRA v3 shows for adult consumers with a maximum of 0.05% substance in the product used, the following exposures:
PC35 0.00735 0.0357 0.153 0.193 0.346
Washing and cleaning products (sentinel)
PROTECTIVE EQUIPMENT
Local exhaust ventilation, protective gloves and safety goggles.
RESPIRATORY EQUIPMENT
None required.
HAND PROTECTION
Protective gloves: Use chemical resistant gloves classified under Standard EN374, class 6.
EYE PROTECTION
Wear approved safety goggles.
HYGIENE MEASURES
Wash at the end of each work shift and before eating, drinking, smoking or using the toilet.
SKIN PROTECTION
Wear protective clothing.
Stability and reactivity
STABILITY
Stable under normal temperature conditions and recommended use.
MATERIALS TO AVOID
Strong oxidising agents, strong reducing agents, strong bases.
HAZARDOUS DECOMPOSITION PRODUCTS
By fire toxic gases (Cox, NOx) may be formed
Disposal considerations
GENERAL INFORMATION
Place into a suitable closed container for disposal as chemical waste.
DISPOSAL METHODS
Dispose of in accordance with local and national regulations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.