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EC number: 400-600-6 | CAS number: 71868-10-5 ACETOCURE 97; GENOCURE*PMP; IGM 4817; IRGACURE 907; SPEEDCURE 97
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1983
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- GLP compliance:
- yes
- Analytical monitoring:
- no
- Buffers:
- pH4: 0.05 M Potassium hydrogenphtalate
pH7: 0.041 M Na2HPO4 + 0.028 M KH2PO4
pH9: 0.043 M Na2B4O7 + 0.017 M KH2PO4 - Details on test conditions:
- Preparation of the test solution:
Pipette 2.00 ml of the solution under study in a 10 ml graduated flask, add 3.0 ml distilled water and fill up to the mark at room temperature with methanol.
Apparatus and conditions:
- Apparatus: Liquid chromatograph
- Column: Nucleosil C 18-10 µm (300 X 4 mm)
- Column temperature: room temperature
- Mobile phase: methanol + water (90 + 10 vol. %)
- Injection volume: 50.0 µl
- Flow rate: 1.00 ml/min
- Analysis time: ca 6 min
- Retention time of the test substance: 4.9 min - Duration:
- 5 d
- pH:
- 4
- Temp.:
- 50 °C
- Duration:
- 5 d
- pH:
- 7
- Temp.:
- 50 °C
- Duration:
- 5 d
- pH:
- 9
- Temp.:
- 50 °C
- Transformation products:
- no
- pH:
- 4
- Temp.:
- 50 °C
- Hydrolysis rate constant:
- < 10
- Remarks on result:
- hydrolytically stable based on preliminary test
- Remarks:
- <10% decomposition at 5 days.
- pH:
- 7
- Temp.:
- 50 °C
- Remarks on result:
- hydrolytically stable based on preliminary test
- Remarks:
- <10% decomposition at 5 days.
- pH:
- 9
- Temp.:
- 50 °C
- Remarks on result:
- hydrolytically stable based on preliminary test
- Remarks:
- <10% decomposition at 5 days.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The test material was considered to be hydrolytically stable at pH 5, 7, & 9 under the conditions of the preliminary test.
Reference
In the test at pH 4, 7 and 9, less than 10 % decomposition was observed after 5 days at 50 °C. The test substance is therefore considered hydrolytically stable.
Description of key information
The study provided was conducted to recognised testing guidelines and with GLP certification.
Key value for chemical safety assessment
Additional information
The potential of the test substance to hydrolyse was investigated in a GLP study according to EEC directive 79/831. At pH 4, 7 and 9, less than 10 % decomposition was observed after 5 days at 50 °C (Ciba-Geigy, 1983a).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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