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Diss Factsheets
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EC number: 231-977-3 | CAS number: 7783-06-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: standard study design, Study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Effects of 10 ppm hydrogen sulfide inhalation on pulmonary function in healthy men and women
- Author:
- Bhambhani,Y, Burnham R, Snydmiller G, et al.
- Year:
- 1 996
- Bibliographic source:
- J. Occup. Environ. Med. 38, 1012-1017
- Reference Type:
- secondary source
- Title:
- Hydrogen sulfide - Interim acute exposure guideline levels (AEGLs) for NAS/COT subcommittee for AEGLs
- Author:
- Anonymous
- Year:
- 2 002
- Bibliographic source:
- http://www.epa.gov/oppt/aegl/pubs/hydrogen_sulfide_interim_nov_2002.pdf
Materials and methods
Test material
- Reference substance name:
- Hydrogen sulphide
- EC Number:
- 231-977-3
- EC Name:
- Hydrogen sulphide
- Cas Number:
- 7783-06-4
- Molecular formula:
- H2S
- IUPAC Name:
- hydrogen sulfide
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Executive summary:
19 healthy volunteers (9 men, 43 age 27.4 +/- 6.4 yr and 10 women, age 21.8 +/- 3.0 yr) were exposed to 0 or 10 ppm hydrogen sulfide for 15 minutes while exercising on a cycle ergonometer at 50% of their VO2max. The exposure protocol is essentially identical to that described by Bhambhani and Singh (1991). There were no treatment-related effects on FVC, FEV1, peak expiratory flow rate, forced expiratory flow rate, or maximal ventilation volume in either sex.
In another study, 28 healthy volunteers (15 men, age 23.4 +/- 5.2 yr and 13 women, age 21.8 +/- 3.0 yr) were exposed to 0 or 10 ppm hydrogen sulfide for 30 minutes while exercising on a cycle ergonometer at 50% of their VO2max. The exposure protocol is essentially identical to that described by Bhambhani and Singh (1991). There were no treatment-related effects on oxygen uptake, carbon dioxide production, respiratory exchange ratio, heart rate, blood pressure, arterial blood oxygen and carbon dioxide tensions. Muscle lactate increased 33% (n.s.) in men and 16% (n.s.) in women after exposure to hydrogen sulfide. Muscle cytochrome oxidase decreased by 16% in men, whereas it increased by 11% in women after exposure to hydrogen sulfide. None of the subjects reported any adverse health effects subsequent to hydrogen sulfide exposure.
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