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Diss Factsheets
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EC number: 233-271-0 | CAS number: 10102-43-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Interacting effects of pH acclimation, pH, and heavy metals on acute and chronic toxicity to Ceriodaphnia dubia (Cladocera)
- Author:
- Belanger SE and Cherry DS
- Year:
- 1 990
- Bibliographic source:
- Journal of Crustacean Biology, 10(2): 225-235.
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Principles of method if other than guideline:
- Daphnids reared in pH 8.0
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Nitric acid
- EC Number:
- 231-714-2
- EC Name:
- Nitric acid
- Cas Number:
- 7697-37-2
- Molecular formula:
- HNO3
- IUPAC Name:
- nitric acid
Constituent 1
- Specific details on test material used for the study:
- HNO3 is degradation product of NO in water so this study expresses the aquatic toxicity of NO.
Sampling and analysis
- Analytical monitoring:
- not specified
- Remarks:
- indirect: pH measurement
Test solutions
- Vehicle:
- yes
- Remarks:
- test material Nitric acid was supplied as a 1% solution (in water presumably)
Test organisms
- Test organisms (species):
- Ceriodaphnia dubia
- Details on test organisms:
- Ceriodaphnia dubia were obtained from US EPA Duluth stock in 1984 from T.J. Norberg and were cultured in water from New River (Virginia).
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 98 mg/L
- Test temperature:
- 25°C
- pH:
- Two tests were conducted at nominal pH values of 3.0, 4.0, 5.0, 6.0, 7.0, 8.0, 9.0, 10.0, 11.0, and 12.0 to determine the pH LC50. pH was adjusted using HNO3
- Nominal and measured concentrations:
- see pH
Results and discussion
Effect concentrations
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 4.6 other: pH
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- other: pH
- Basis for effect:
- mortality
- Details on results:
- Ceriodaphnia dubia cultured at pH 8.0 suffered 100% mortality at pH 3.2-3.4. The individual 48-h LC50s for acidic pH were 4.4 and 4.7. Grand probits (analyses combined) were 4.6 for acid pH.
Applicant's summary and conclusion
- Conclusions:
- Ceriodaphnia dubia cultured at pH 8.0 suffered 100% mortality at pH 3.2-3.4. The 48-h LC50 was pH=4.6.
HNO3 is degradation product of NO in water so this result expresses the aquatic toxicity of NO.
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