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Diss Factsheets
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EC number: 215-290-6 | CAS number: 1319-46-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to soil macroorganisms except arthropods
Administrative data
- Endpoint:
- toxicity to soil macroorganisms except arthropods: long-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study is performed according to OECD guidelines with some deviations Comparable to guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- publication
- Title:
- Is the OECD acute worm toxicity test environmentally relevant? The effect of mineral form on calculated lead toxicity
- Author:
- Nicola A. Davies, Mark E. Hodson, Stuart Black
- Year:
- 2 002
- Bibliographic source:
- Environmental Pollution 121, 49-54
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 222 (Earthworm Reproduction Test (Eisenia fetida/Eisenia andrei))
- Deviations:
- yes
- Principles of method if other than guideline:
- The toxicity of lead to worms in soil was determined following the draft OECD earthworm reproduction toxicity protocol except that lead was added as solid lead nitrate, carbonate and sulphide rather than as lead nitrate solution as would normally be the case.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Lead carbonate
- EC Number:
- 209-943-4
- EC Name:
- Lead carbonate
- Cas Number:
- 598-63-0
- Molecular formula:
- CH2O3.Pb
- Details on test material:
- - Name of test material (as cited in study report): lead carbonate
- Molecular formula (if other than submission substance): PbCO3
- Physical state: fine powder
- Analytical purity: >99%
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test substrate
- Vehicle:
- not specified
- Details on preparation and application of test substrate:
- - Method of mixing into soil (if used): 40°C overnight
Test organisms
- Test organisms (species):
- Eisenia fetida
- Animal group:
- annelids
- Details on test organisms:
- TEST ORGANISM
- Common name: Tiger Worm
- Source: Blades Biological (Cowden, Edenbridge, Kent, UK)
- Age at test initiation (mean and range, SD): 3 months old
- Weight at test initiation (mean and range, SD): 290-470 mg
ACCLIMATION
- Acclimation period: 1 wk
- Acclimation conditions (same as test or not): metal free test soil
Study design
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- no
- Total exposure duration:
- 28 d
Test conditions
- Details on test conditions:
- TEST SYSTEM
- Amount of soil or substrate: 500 g dry soil
- No. of organisms per container (treatment): 10
- No. of replicates per treatment group: 4
- No. of replicates per control: 8
SOURCE AND PROPERTIES OF SUBSTRATE (if soil)
- Geographic location: Turf Management Systems, Iver Heath, Buckinghamshire, UK
- Sampling depth (cm): <2mm
- Composition (if artificial substrate):
- Organic carbon (%): 2.8
- Maximum water holding capacity (in % dry weigth): 48
- CEC: 17.6 Meq 100 g-1
- Pretreatment of soil: sterilised
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : mortality after each 7-day period - Nominal and measured concentrations:
- Nominal: 625, 1200, 3125,, 5000, 6250, 8000 and 12500 µg Pb/g soil
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 28 d
- Dose descriptor:
- LC50
- Effect conc.:
- > 12 500 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: calculated using Trimmed Spearman-Karber stat
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- > 12 500 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: calculated by ANOVA
- Duration:
- 28 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 12 500 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: weight change
- Remarks on result:
- other: calculated using the Linear Interpolation Method
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- > 12 500 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: weight change
- Remarks on result:
- other: calculated using the Linear Interpolation Method
- Duration:
- 28 d
- Dose descriptor:
- EC50
- Effect conc.:
- 8 604 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: cocoon production
- Remarks on result:
- other: calculated using the Linear Interpolation Method
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 8 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: cocoon production
- Remarks on result:
- other: calculated using the Linear Interpolation Method
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- In the conditions of the study, lead carbonate was found non toxic due for the most part to its low bioavailability.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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