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EC number: 253-568-9 | CAS number: 37609-25-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Study Plan Signed 21 January 1997 - Final Report emission 27 February 1997; Experimental Phase : 21 January 1997 to 19 February 1997.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 1997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- (E)-cyclohexadec-5-enone
- Cas Number:
- 35951-24-7
- Molecular formula:
- C16H28O
- IUPAC Name:
- (E)-cyclohexadec-5-enone
- Reference substance name:
- (Z)-cyclohexadec-5-enone
- Cas Number:
- 21944-95-6
- Molecular formula:
- C16H28O
- IUPAC Name:
- (Z)-cyclohexadec-5-enone
Constituent 1
Constituent 2
- Specific details on test material used for the study:
- Name (as stated in the report): Ambretone
Batch: 261997
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- The sludge is collected in the morning, washed three times in the mineral medium (by centrifuging at 1000 g for 10 minutes, discarding the supernatant and resuspending in mineral medium) and kept aerobic until being used on the same day.
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- other: nominal test substance concentration
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
Reference substance
- Reference substance:
- other: Sodium benzoate
- Remarks:
- 99% purity
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 86
- Sampling time:
- 28 d
- Details on results:
- Oxygen uptakes, as read on the SAPROMAT meters are corrected:
- by deducting the basic oxygen uptake of sludge blank samples (Flasks 2/3 and 2/4)
- proportionally to account for the differences between actual and nominal concentrations of test and reference substance
BOD5 / COD results
- Results with reference substance:
- Degradation of Sodium Benzoate exceeds 40% after 7 days and 65% after 14 days (observed 72% biodegradation on Day 7 and 83% on Day 14): the activity of the inoculum is thus verified and the test is considered valid.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Ambretone undergoes 86% biodegradation after 28 days in the test conditions. Biodegradation starts (exceeds 10%) on day 3 (11% biodegradation) and reaches 72% at the end of the 10-day window (days 3 to 13).
Thus, Ambretone should be regarded as readily biodegradable according to this test.
The curves obtained with the reference substance alone and with Ambretone + reference substance show no toxic effect of Ambretone on the micro-organism at the test concentration. - Executive summary:
The Ready Biodegradability of Ambretone was determined by the Manometric Respirometry Test according to the OECD guideline 301F.
Ambretone undergoes 86% biodegradation after 28 days in the test conditions. Biodegradation starts (exceeds 10%) on day 3 (11%) and reaches 72% at the end of the 10-day window (days 3 to 13).
Thus, Ambretone should be regarded as readily biodegradable according to this test.
At the concentration used in the test (100 mg/L), Ambretone is not inhibitory to the micro-organisms.
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