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EC number: 213-103-2 | CAS number: 924-42-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1991
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Well documented report of a guideline study conducted to GLP.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- N-(hydroxymethyl)acrylamide
- EC Number:
- 213-103-2
- EC Name:
- N-(hydroxymethyl)acrylamide
- Cas Number:
- 924-42-5
- Molecular formula:
- C4H7NO2
- IUPAC Name:
- N-(hydroxymethyl)acrylamide
- Details on test material:
- The test article was identified as CT-444-90E, containing 40-44% N-Methylolacrylamide in water (with < 5% acrylamide and < 3% formaldehyde).
Test Substance: H20 (~50-54%), C4H7O2N (~40-44%), C3H5NO (<5“%), CH2O (<3%), C7H8O2 (~0.003%), Cu.H2O4S (~0.0002%). Carbon content was 23.7%.
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of activated sludge: Bergen Co., New Jersey
- Storage conditions: no data given
- Storage length: no data given
- Concentration of sludge: no data given
- Initial cell/biomass concentration: no data given
- Water filtered: no data given
- Type and size of filter used, if any: no data given - Duration of test (contact time):
- ca. 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- ca. 1 mg/L
- Based on:
- test mat.
- Initial conc.:
- ca. 2 mg/L
- Based on:
- test mat.
- Initial conc.:
- ca. 5 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Stock solution was prepared by adding 2 g of sample to 1 liter of distilled water. The stock solution was screened to determine if it had a similar
percent carbon content as stated in the formula provided by the supplier. Stock solution was diluted to 100 ppm as carbon after analysis. The diluted
stock was then added to BOD bottles at 3.33 ml, 6.67 ml and 16.65 ml to yield test concentrations of 1 mg, 2 mg and 5 mg as carbon, respectively.
Test solutions were inoculated with a low concentration of microorganisms from a mixed population and kept in closed bottles in the dark at a constant
temperature of 20 ± 1° C. The activated sludge bacteria was from Bergen Co., New Jersey.
The degradation was followed by oxygen analyses with the YSI Dissolved Oxygen Analyzer 54A over a 28-day period.
Degradability was based on a comparison of readings of actual oxygen demand to the theoretically expected oxygen demand.
A parallel control with inoculum, but without test material, was run as a blank correction factor.
The procedure was validated by means of a reference substance (aniline, 2 mg/l) of known biodegradability.
Reference substance
- Reference substance:
- aniline
- Remarks:
- 2mg/L
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 15 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 16.7
- Sampling time:
- 15 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 51.9
- Sampling time:
- 28 d
BOD5 / COD results
- Results with reference substance:
- Aniline: day 5 = 18.5 %, day 15 = 66.7 %, day 28 = 98.1 %
Any other information on results incl. tables
Sample conc. (mg/l) |
Degradation at: |
||
5 days |
15 days |
28 days |
|
1 |
0% |
0% |
40.7% |
2 |
0% |
16.7% |
51.9% |
5 |
0% |
14.8% |
40.7% |
Average |
0% |
10.5% |
44.3% |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable
- Conclusions:
- Under the test conditions, the test substance was not readily biodegradable (51.9% in 28 days)
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