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Diss Factsheets
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EC number: 237-396-1 | CAS number: 13770-89-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
General Information
- Name:
- Nickel Sulphamate
- Implementation:
- EU
- Type of classification:
- harmonised classification
- Remarks:
- Ni sulphamate has not previously been classified for acute oral or inhalation toxicity in the EU. However, a recently completed OECD-guideline compliant study reported an oral LD50=1098 mg/kg Ni sulphamate. Based on this newly generated data, Ni sulphamate now has a harmonized classification as Acute Tox. 4; H302 according to the 14th ATP to the CLP Regulation. In addition, a comprehensive read-across assessment was recently completed based on bioaccessibility data in synthetic lung fluids of various nickel compounds combined in vivo verification data for three source nickel substances. The bioaccessibility-based paradigm presented in a summary document in Section 7.2.2 and Appendix B2 of the CSR enables grouping of target Ni substances for classification purposes according to bioaccessibility in interstitial fluid as demonstrated. The outcome of this assessment indicates that Ni sulphamate should be read-across from Ni sulphate for acute inhalation toxicity. Therefore, application of this read-across paradigm suggests that Ni sulphamate should be classified as Acute Tox 4.; H332. This nickel sulphamate classification profile reflects a newly harmonized (according to the 14th ATP to the CLP) acute oral classification of Acute Tox. 4; H302 and an acute inhalation self-classification of Acute Tox. 4; H332.
- In the Labelling section, the hazard pictogram GHS08 (health hazard), associated with the respiratory sensitization 1 classification, overrides the hazard pictogram GHS07 (exclamation mark) for skin sensitization 1 according to the Guidance on Labelling and Packaging in accordance with Regulation (EC) No 1272/2008.
Related composition
- Related composition:
- Nickel sulphamate
Classificationopen allclose all
Explosives
- Reason for no classification:
- data conclusive but not sufficient for classification
Flammable gases and chemically unstable gases
- Reason for no classification:
- data conclusive but not sufficient for classification
Aerosols
- Reason for no classification:
- data conclusive but not sufficient for classification
Oxidising gases
- Reason for no classification:
- data conclusive but not sufficient for classification
Gases under pressure
- Reason for no classification:
- data conclusive but not sufficient for classification
Flammable liquids
- Reason for no classification:
- data conclusive but not sufficient for classification
Flammable solids
- Reason for no classification:
- data conclusive but not sufficient for classification
Self-reactive substances and mixtures
- Reason for no classification:
- data conclusive but not sufficient for classification
Pyrophoric liquids
- Reason for no classification:
- data conclusive but not sufficient for classification
Pyrophoric solids
- Reason for no classification:
- data conclusive but not sufficient for classification
Self-heating substances and mixtures
- Reason for no classification:
- data conclusive but not sufficient for classification
Substances and mixtures which in contact with water emit flammable gases
- Reason for no classification:
- data conclusive but not sufficient for classification
Oxidising liquids
- Reason for no classification:
- data conclusive but not sufficient for classification
Oxidising solids
- Reason for no classification:
- data conclusive but not sufficient for classification
Organic peroxides
- Reason for no classification:
- data conclusive but not sufficient for classification
Corrosive to metals
- Reason for no classification:
- data lacking
Desensitized explosives
- Reason for no classification:
- data lacking
Acute toxicity - oral
- Hazard category:
- Acute Tox. 4
- Hazard statement:
- H302: Harmful if swallowed.
Acute toxicity - dermal
- Reason for no classification:
- data conclusive but not sufficient for classification
Acute toxicity - inhalation
- Hazard category:
- Acute Tox. 4
- Hazard statement:
- H332: Harmful if inhaled.
Skin corrosion / irritation
- Reason for no classification:
- data conclusive but not sufficient for classification
Serious eye damage / eye irritation
- Reason for no classification:
- data conclusive but not sufficient for classification
Respiratory sensitisation
- Hazard category:
- Resp. Sens. 1
- Hazard statement:
- H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Skin sensitisation
- Hazard category:
- Skin Sens. 1
- Hazard statement:
- H317: May cause an allergic skin reaction.
Aspiration hazard
- Reason for no classification:
- data lacking
Reproductive toxicity
- Hazard category:
- Repr. 1B
- Hazard statement:
- H360D: May damage the unborn child.
- Specific effect:
- Perinatal mortality
Effects on or via lactation
- Reason for no classification:
- data conclusive but not sufficient for classification
Germ cell mutagenicity
- Hazard category:
- Muta. 2
- Hazard statement:
- H341: Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
Carcinogenicity
- Hazard category:
- Carc. 1A
- Hazard statement:
- H350i: May cause cancer by inhalation.
- Route of exposure:
- inhalation
1. Specific target organ toxicity - single (STOT-SE)
- Reason for no classification:
- data conclusive but not sufficient for classification
1. Specific target organ toxicity - repeated (STOT-RE)
- Hazard category:
- STOT Rep. Exp. 1
- Hazard statement:
- H372: Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Affected organs:
- lungs
- Route of exposure:
- inhalation
1.
- Concentration range (%):
- >= 0.01
- Hazard categories:
- Skin Sens. 1
2.
- Concentration range (%):
- >= 1
- Hazard categories:
- STOT Rep. Exp. 1
3.
- Concentration range (%):
- >= 0.1 - < 1
- Hazard categories:
- STOT Rep. Exp. 2
Hazardous to the aquatic environment (acute / short-term)
- Hazard category:
- Aquatic Acute 1
- Hazard statement:
- H400: Very toxic to aquatic life.
Hazardous to the aquatic environment (long-term)
- Hazard category:
- Aquatic Chronic 1
- Hazard statement:
- H410: Very toxic to aquatic life with long lasting effects.
- M-Factor acute:
- 1
- M-Factor chronic:
- 1
Hazardous to the ozone layer
- Reason for no classification:
- data conclusive but not sufficient for classification
Labelling
- Signal word:
- Danger
Hazard pictogram
- GHS07: exclamation mark
- GHS08: health hazard
- GHS09: environment
Hazard statements
- H302: Harmful if swallowed.
- H332: Harmful if inhaled.
- H350i: May cause cancer by inhalation.
- H341: Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- H360D: May damage the unborn child.
- Perinatal mortality
- H372: Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- H317: May cause an allergic skin reaction.
- H410: Very toxic to aquatic life with long lasting effects.
Notes
- Note H
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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