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EC number: 201-291-9 | CAS number: 80-56-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2010-05-26 to 2010-09-21
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted according to OECD 104 and EU A.4 guidelines, under GLP without deviation and with certificate of analysis included.
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- static method
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 690 Pa
- Temp.:
- 25 °C
- Vapour pressure:
- 851 Pa
- Conclusions:
- Using the static method according to guideline OECD 104 and EU method A.4, vapour pressures of 690 Pa at 20 °C and 851 Pa at 25 °C were estimated for the test item.
These values were calculated from the regression of 22 individual measurements. - Executive summary:
Vapour pressure of alpha-pinene multiconstituent was measured using static method according to OECD guideline 104 and EU method A.4. Thanks to the equation log P = B*1/T + A and the linear regression parameters of 22 individual measurements between 20.9 and 55.3 °C, the vapour pressure of the test item was calculated as 690 Pa at 20.0 °C and as 851 Pa at 25.0 °C.
The correlation coefficient r being -0.9963, the linear regression is very good and the results are considered as valid. No observations were made which might cause doubts concerning the validity of the study outcome.
- Endpoint:
- vapour pressure
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Justification for type of information:
- α-Pinene is a bicyclic monounsaturated monoterpene and (-)-α-pinene is an enantiomeric form of α-pinene. Therefore, data on (-)-alpha pinene can be extrapolated to alpha-pinene. (see read-across justification document in section 13).
- Reason / purpose for cross-reference:
- read-across source
- Test no.:
- #1
- Temp.:
- 293.15 K
- Vapour pressure:
- ca. 567 Pa
- Remarks on result:
- other: First trial
- Test no.:
- #1
- Temp.:
- 298.15 K
- Vapour pressure:
- ca. 679 Pa
- Remarks on result:
- other: First trial
- Test no.:
- #2
- Temp.:
- 293.15 K
- Vapour pressure:
- ca. 558 Pa
- Remarks on result:
- other: Second trial
- Test no.:
- #2
- Temp.:
- 298.15 K
- Vapour pressure:
- ca. 624 Pa
- Remarks on result:
- other: Second trial
- Temp.:
- 293.15 K
- Vapour pressure:
- ca. 563 Pa
- Remarks on result:
- other: Mean
- Temp.:
- 298.15 K
- Vapour pressure:
- ca. 652 Pa
- Remarks on result:
- other: Mean
- Conclusions:
- Using the static method according to guideline OECD 104 and method EU A.4, vapour pressure of 563 Pa at 20°C and 652 Pa at 25°C were estimated for the test item.
- Executive summary:
Vapour pressure of (-)-alpha-pinene was measured using the static method according to guideline OECD 104 and method EU A.4.
The Log10(Vapour Pressure (Pa)) was plotted against 1/T (K) and a linear function was obtained. With this equation, the vapour pressure has been calculated for temperatures at 20°C and 25°C.
The vapour pressure of the test item was calculated as 563 Pa at 20°C and 652 Pa at 25°C.
Based on the correlation coefficient R² over 0.95 and on the difference between the two determinations at each temperature (< 20%), the study is considered as valid.
Referenceopen allclose all
The calculation results are presented in the following table:
n |
t |
P |
T |
1/T |
log(P) |
|
°C |
mbar |
K |
1/K |
log Pa |
1 |
20.9 |
7.0 |
294.05 |
0.00340078 |
2.8451 |
2 |
22.0 |
7.4 |
295.15 |
0.00338811 |
2.8692 |
3 |
26.8 |
8.7 |
299.95 |
0.00333389 |
2.9395 |
4 |
34.2 |
11.7 |
307.35 |
0.00325362 |
3.0682 |
5 |
37.3 |
13.2 |
310.45 |
0.00322113 |
3.1206 |
6 |
38.9 |
14.3 |
312.05 |
0.00320461 |
3.1553 |
7 |
43.0 |
16.6 |
316.15 |
0.00316306 |
3.2201 |
8 |
43.8 |
17.1 |
316.95 |
0.00315507 |
3.2330 |
9 |
45.0 |
17.9 |
318.15 |
0.00314317 |
3.2529 |
10 |
48.8 |
20.8 |
321.95 |
0.00310607 |
3.3181 |
11 |
54.5 |
25.5 |
327.65 |
0.00305204 |
3.4065 |
12 |
55.3 |
26.6 |
328.45 |
0.00304460 |
3.4249 |
13 |
52.4 |
24.5 |
325.55 |
0.00307172 |
3.3892 |
14 |
50.7 |
23.1 |
323.85 |
0.00308785 |
3.3636 |
15 |
48.6 |
21.3 |
321.75 |
0.00310800 |
3.3284 |
16 |
44.3 |
18.2 |
317.45 |
0.00315010 |
3.2601 |
17 |
41.0 |
16.0 |
314.15 |
0.00318319 |
3.2041 |
18 |
36.6 |
13.6 |
309.75 |
0.00322841 |
3.1335 |
19 |
35.1 |
12.8 |
308.25 |
0.00324412 |
3.1072 |
20 |
31.4 |
11.3 |
304.55 |
0.00328353 |
3.0531 |
21 |
27.6 |
10.0 |
300.75 |
0.00332502 |
3.0000 |
22 |
24.0 |
8.9 |
297.15 |
0.00336530 |
2.9494 |
Linear Regression Parameters
Parameter |
Value |
Slope B |
-1584.44 |
Intercept A |
8.244 |
Correlation coefficient r |
-0.9963 |
Using the equation log P = B*1/T + A, values of vapour pressure at 20 and 25 °C were calculated.
First trial:
Vapour Pressure (Pa) |
Time (hh:mn) |
Corresponding Temperature (°C) |
Temperature (K) |
1/T (K-1) |
Log10(p) |
650 |
14:35 (21/09/16) |
23.6 |
296,75 |
3,370E-03 |
2,813 |
705 |
10:30 |
25.9 |
299,05 |
3,344E-03 |
2,848 |
740 |
15:00 |
28.0 |
301,15 |
3,321E-03 |
2,869 |
810 |
16:40 |
30.3 |
303,45 |
3,295E-03 |
2,908 |
890 |
18:00 |
32,5 |
305,65 |
3,272E-03 |
2,949 |
A plot of Log10(p) versus temperature (1/T) (with p in Pa and T in K) gives the following statistical data using an unweighted least square treatment.
Slope -1361.7
Intercept 7.3988
R² 0.9894
The results obtained indicate the following vapour pressure relationship:
Log10(p (Pa)) = -1361.7 / T (K) + 7.3988
The above equation yields a vapour pressure of 567 Pa at 293.15 K and 679 Pa at 298.15 K.
Second trial:
Vapour Pressure (Pa) |
Time (hh:mn) |
Corresponding Temperature (°C) |
Temperature (K) |
1/T (K-1) |
Log10(p) |
610 |
10:40 |
23,6 |
296.75 |
3,370E-03 |
2,785 |
633 |
12:00 |
25,8 |
298.95 |
3,345E-03 |
2,801 |
662 |
14:00 |
28 |
301.15 |
3,321E-03 |
2,821 |
699 |
15:20 |
30.3 |
303.45 |
3,295E-03 |
2,844 |
742 |
16:40 |
32,6 |
305.75 |
3,271E-03 |
2,870 |
A plot of Log10(p ) versus reciprocal temperature (1/T) (with p in Pa and T in K) gives the following statistical data using an unweighted least square treatment.
Slope -859.99
Intercept 5.6799
R² 0.9916
The results obtained indicate the following vapour pressure relationship:
Log10(p (Pa)) = -859.99 / T(K) + 5.6799
The above equation yields a vapour pressure of 558 Pa at 293.15 K and 624 Pa at 298.15 K.
Description of key information
Vapour pressure of alpha-pinene multiconstituent was calculated using the static method (from the regression of 22 individual measurements):
690 Pa at 20°C
851 Pa at 25°C
Key value for chemical safety assessment
- Vapour pressure:
- 690 Pa
- at the temperature of:
- 20 °C
Additional information
A study was conducted according to OECD 104 and EU A.4 guidelines to measure vapour pressure of alpha-pinene multiconstituent. As the results were obtained under GLP without deviation, they were considered as valid and reliable without restriction and used to propose a key value.
This result is supported by consistent experimental data obtained with (-)-alpha-pinene.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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