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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 401-680-5 | CAS number: 125304-04-3 TINUVIN 171; TINUVIN 571
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu./o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_environmental-fate-and-pathways.png)
Endpoint summary
Administrative data
Description of key information
Additional information
Hydrolysis:
In accordance with column 2 of REACH Annex VIII, a test on hydrolysis (required in section 9.2.2.1) does not need to be conducted as the substance is highly insoluble in water (< 3E-04 g/L). Furthermore, the substance does not contain any functional groups that are susceptible to hydrolysis.
Biodegradation:
According to the key study (CIBA, 1986) the ready biodegradability of the test item was assessed over a 28 day period by the modified Sturm test (OECD 301B). The results of this study indicates that the test item cannot be classified readily biodegradable under conditions of the test. These results were supported by a water-sediment study (OECD 308) where no significant degradation of the test item was observed and the substance was concluded to be persistent (P). QSAR calculations predicted 126 possible metabolites including the main structures of the substance.
Accorrding to the key study (BASF 2020) the biodegradation in sediment and water was assessed (OECD 308). As a result the test substance can not be considered as readily biodegradable. In this study 31 metabolites in quantities >= 0.1 % but well below 10% were observed, although the amount of 27 metabolites was far below any quantity that allows for a identification of the compound. However, four of them could be identified and were thus subsequently analysis for its PBT/vPvB properties (see chapter 5.2 for further details and chapter 2.3 for overall conclusion)
Bioaccumulation:
The bioaccumulation and depuration of the test item were studied with 14C-labeled test substance in rainbow trout maintained in a continous flow-through system in accordance with OECD guideline 305. Mean bioconcentration factors at steady-state were in the range 66 - 179. Accumulation of radioactive residues was in the order edible < whole-fish < non-edible tissues and well below 1000, therefore the test item is not considered to be bioaccumulative. Elimination of the test item during the depuration phase was relatively slow. Kinetic analysis indicated that approximately 90% of the radioactive residues were eliminated in 36 - 44 days. Additionally, QSAR calculations confirmed no bioaccumulation potential for the predicted and identified metabolites measured in the OECD 308 study (BCF corrected from 2.69 to 363 l/kg) .
Adsorption/Desorption:
Adsorption/Desoprtion of the test item on soil was determined in a study according to OECD Guideline 106. As a result of this study the following estimation of the adsorption-coefficient (log Koc) of the test substance could be made: log Koc is higher than 5.6.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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