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Diss Factsheets
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EC number: 201-039-8 | CAS number: 77-58-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The following study has been submitted to address the toxicity to aquatic algae and cyanobacteria endpoint:
Steger-Hartmann, T. (1999). Growth inhibition test of di-n-butyltin dilaurate (ZK 21976) on the green algae Scenedesmus subspicatus. Research Report No. IC29. Berlin, Germany. Testing laboratory: Schering AG, Experimentelle Toxikologie. Report no.: IC29. Study number: TXST19980233. Report date: 1999-02-17.
A reliability rating of 2 was assigned to this study, according to the criteria of Klimisch, 1997 as the study was conducted in accordance with generally accepted scientific principles, possibly with incomplete reporting or methodological deficiencies, which do not affect the quality of the relevant results. This study was chosen as the key study. Result: No EC50 could be determined, however nominal loading rate was 100 mg/L, so EC50 is considered to be >100 mg/L loading rate (>1 mg/L).
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1 mg/L
Additional information
Di-n-butyltin-dilaurate had a slight inhibitory effect on the growth of Scenedesmus subspicatus at all chosen dilutions after 72 h. However, the effect showed no concentration dependence and did not exceed a 27% inhibition of the biomass integral and 16% inhibition of the growth rate. Concomitant tin analysis indicated that the calculation of the di-n-butyltin dilaurate concentration on the basis of TOC led to an overestimation in all dilutions. The tin content displayed a non-linear dilution behaviour, revealing extreme inhomogeneity of the test substance.
Due to the lack of dose-dependence the EbC50 (biomass) and the ErC50 (growth rate) could not be calculated. A NOEC value could not be established.
Since the observed inhibition was small even at the highest concentrations, it is concluded, that a saturated solution of di-n-butyltin dilaurate is not very toxic to the green algae Scenedesmus subspicatus.
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