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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 201-159-0 | CAS number: 78-93-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: A sufficiently well reported study to be able to judge result as reliable. This study examined many chemicals and has been judged reliable by the OECD during the assessment of a number of chemical substances under the OECD HPV programme
Data source
Reference
- Reference Type:
- publication
- Title:
- Brine Shrimp Bioassay and Seawater BOD of Petrochemicals.
- Author:
- Price KS, Waggy GT, and Conway RA
- Year:
- 1 974
- Bibliographic source:
- Journal Water Pollution Control Federation 46(1): 63-77
Materials and methods
- Principles of method if other than guideline:
- Closed bottle test (BOD of ThOD) according to the "Standard Methods for the Examination of Water and Wastewater." 13th Ed., Amer. Pub. Health Assn., New York, 1971.
- GLP compliance:
- no
Test material
- Reference substance name:
- Butanone
- EC Number:
- 201-159-0
- EC Name:
- Butanone
- Cas Number:
- 78-93-3
- Molecular formula:
- C4H8O
- IUPAC Name:
- butan-2-one
- Details on test material:
- - Test substance: Methyl ethyl ketone
- Analytical Purity: no data
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): no data
- Water filtered: yes
- Type and size of filter used, if any: glass wool
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Settled domestic wastewater was filtered through glass wool and added (3 ml) as seed material to BOD bottles that were half filled with aerated dilution water containining minerals and buffer. An aliquot of the test substance was added to the BOD bottles from a 0.1% stock solution to yieldthe specified starting concentrations. At least two concentrations were tested in duplicate.
Dissolved oxygen (DO) was determined 5 times during the study period (20 days) in individual BOD bottles using a commercial DO meter equipped with a probe. If the DO was 4.0 mg/l, the contents of the bottle were aerated to return the DO to at least 7 mg/l. 2-ml samples were collected from each bottle and analyzed for nitrites and nitrates; although no attempt was made to inhibit the nitrification process.
The results of the biodegradation tests were expressed as percent bio-oxidation.
Synthetic saltwater was prepared in accordance with Standard Methods (1971).
The seed material was obtained from Lavaca Bay, Texas. A small amount of raw wastewater was added to the seed material approximately every 3-4 days. Distilled water was added to compensate for evaporative loss.
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (O2 consumption)
- Value:
- 76
- Sampling time:
- 5 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 82
- Sampling time:
- 10 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 84
- Sampling time:
- 15 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 89
- Sampling time:
- 20 d
Applicant's summary and conclusion
- Interpretation of results:
- readily biodegradable
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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