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Diss Factsheets
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EC number: 203-806-2 | CAS number: 110-82-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu./o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_environmental-fate-and-pathways.png)
Monitoring data
Administrative data
- Endpoint:
- monitoring data
- Type of information:
- other: Regulatory review
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data are taken from a regulatory review document and therefore, although the original data have not been reviewed, the data are considered to be reliable.
Data source
Reference
- Reference Type:
- other:
- Title:
- European Risk Assessment Report for cyclohexane
- Author:
- European Chemical Bureau
- Year:
- 2 004
- Bibliographic source:
- European Chemical Bureau, EUR 21015 EN
Materials and methods
- Principles of method if other than guideline:
- We have not seen these individual studies, but the data were reviewed and compiled for the EU RAR (2004) and so, taken together, the data represents the range of concentrations measured in various situations.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Cyclohexane
- EC Number:
- 203-806-2
- EC Name:
- Cyclohexane
- Cas Number:
- 110-82-7
- Molecular formula:
- C6H12
- IUPAC Name:
- cyclohexane
- Details on test material:
- No data reported
Constituent 1
Study design
- Details on sampling:
- No data reported
Results and discussion
- Details on results:
- Further evidence to support abiotic and biotic degradation is available from field monitoring studies where cyclohexane has been detected in surface water or effluents at very low concentrations indicating that it is easily biodegraded.
Any other information on results incl. tables
Table 3.11 from EU RAR (2004) Monitoring of cyclohexane in effluents or surface water | ||||
Location | Year | Results (µg/l) | Remarks | Reference |
The Netherlands, river Rhine | 1978 | 0.03-1 | 2 locations, n = ? | Morra et al. (1979) |
Japan, surface water | 1979 | 0.2 | n = 27, no positive results, d.l.: 0.05-0.2 µg/l | Environment Agency (1996) |
USA, 14 heavily industrialised river basins |
1977 | 0-4 | n = 204, 13 positive results, d.l.: 1 µg/l | US EPA (1977) |
USA, Gulf of Mexico |
1977 | open sea:0-0.003 | n = 6 | Sauer (1981a) |
coastal sea: 0.003-0.02 | n = 4 | |||
USA, Embarras river, crude oil production area | 1975-1977 | average: 0.6 | n = 16, d.l.: 0.1 µg/l | Siefker and Catt (1980) |
maximum: 2.3 | ||||
UK, Mersey estuary and its freshwater inputs |
1987/88 | freshwater: positive: 3/17 | qualitative results only, no detection limit given | FWR (1990) |
suspended matter: 3/17 | ||||
estuary: positive: 9/23 | ||||
suspended matter: 16/23 | ||||
USA, plume of a hydrocarbon venting system from an oil platform | 1981 | 0.4 | n = 1 | Sauer (1981b) |
USA, wastewater from am oil platform |
1981 | 100 | n = 1 | Sauer (1981b) |
USA, effluents from chemical manufacturing sites | 1976-1978 | 3 positive results at concentrations 10 µg/l | n = 63 | Perry et al. (1979) |
Table 3.16 from EU RAR (2004) Monitoring of cyclohexane in the atmosphere |
||||
Location | Year | Results (µg/m3) | Remarks | Reference |
Oxfordshire, UK, 30 m from an infrequently used road | 5/1986-3/1987 | 0.14-1.43 | n = 127, 77 samples below d.l. | Jones (1988) |
The Netherlands, in the vicinity of over 300 homes in Ede and Rotterdam | 1981-1983 | median: 0.4 | n > 300 | Lebret et al. (1986) |
max.: 2 | ||||
Austria, region of Vienna |
10/1986-2/1987 | urban (street level): 6.21 | n = 17 (average) | Lanzerstorfer and Puxbaum (1990) |
urban (elev. 52 m): 2.72 | n = 12 (average) | |||
suburbs: 1.75 | n = 16 (average) | |||
semi-rural: 0.68 | n = 9 (average) | |||
Norwegian Arctic |
Jul-82 | 0.07 (d.l.) | n = 9 | Hov et al. (1984) |
Mar-83 | 0.189 | n = 10 (average) | ||
USA, Houston, Texas | 1973/1974 | downtown Houston: 10-19 | n = 2 | US EPA (1979a) |
industrial area: 0-130.3 | n = 14 | |||
USA, Texas, State Forest |
1978 | range: 0.3-3.2 | n = 14 | US EPA (1979b) |
average: 1.58 | ||||
USA, Los Angeles | Sept./Nov. 1981 | range: 24.4-108.2 | n = 23 | Grosjean and Fung (1984) |
USA, urban, industrial & rural areas |
1980 | urban: 0-3.2 | n = 6 | Arnts and Meeks (1981) |
oil shale devel. area: 0.1-0.6 | n = 5 | |||
rural area: 0-1.2 | n = 9 | |||
refinery: 8.7; 14.4 | ||||
nat. gas facility: 31 | ||||
USA, 7 cities | range: 0.35-108.2 | Beals et al. (1986) | ||
USA, 39 cities | 1984-1986 | range: 0.19-396.7 | n > 800, sampling June - Sept. each year | Seila and Lonneman (1988) |
median: 2.13 | ||||
75-percentile: 4.7 | ||||
USA, New Jersey, inside road tunnel | 1972 | average: 55.6 | n = 2 | Lonneman et al. (1986) |
1982 | average: 44.2 | n = 28 | ||
Australia, Sydney downwind of refinery complex and downwind of business district | 1979/1980 | average: 3.14 | 3 sites, n = 140 | Nelson and Quigley (1982) |
Japan, Tokyo, flight path to airport, altitude 350-600 m | 1980 | average: 0.35 | n = 66 | Uno et al. (1985) |
Applicant's summary and conclusion
- Conclusions:
- Further evidence to support abiotic and biotic degradation is available from field monitoring studies where cyclohexane has been detected in surface water or effluents at very low concentrations (EU RAR 2004) indicating that it is easily biodegraded.
- Executive summary:
The results were taken from the EU RAR for cyclohexane (2004). Although the original sources have not been reviewed, the data are considered to be reliable as they are taken from a peer-reviewed regulatory document.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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