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Diss Factsheets
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EC number: 205-634-3 | CAS number: 144-62-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: No guideline study used but comparable to national guidelines/standards
- Qualifier:
- according to guideline
- Guideline:
- other: Deutsche Einheitsverfahren zur Wasser, Abwasser und Schlamm-Untersuchung L 15 Fischtest
- GLP compliance:
- no
- Analytical monitoring:
- no
- Details on sampling:
- The test medium and control were not sampled prior to, during and after the exposure period
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Chemicals:
Calcium solution, 0,5 M: 109,55 g calciumchloride-6-hydrate, CaCl2 6H20, clean crist., is solved in deionized water and completed to a volume of 1L, 1 ml of the solution contains 0,5 mmol calcium-ions.
Magnesium solution, 0,5 M: 123,25 g magnesiurnsulfate-7-hydrate, MgSO4.7 H2O, clean krist., is solved in deionized water; the solution is completed to a volume of 1 L with deionized water. 1 ml of the solution contains 0,5 mmol magnesium-ions.
Hydrogencarbonate solution, 1 M: 84,01 g potassiumhydrogencarbonate, NaHCO8, clean, is solved in deionized water; the solution is completed to a volume of 1 L with deionized water. 1 ml of the solution has an acid capacity of 4,3 (formerly known as m-value) mmol/L when completed to a volume of 1 L water.
Sulfic acid, 1 N; 1 ml of the solution has an acid capacity of 4,3 mmol/L when completed to a volume of 1 L water.
Testing water: for the study chloric free drinking water from a local source was used with a concentration of calcium-magnesium-ions of (2,7 ± 0,5) mmol/1 - corresponding to (15 ± 3) °d; the ratio of calcium- to magnesium-ions needs to be approx. 4 to 1.
The acid capacity 4,3 needs to be 0,7 to 0,9 mmol/1 - corresponding to 2,0 to 2,5 °KH - and the pH-value needs to be between 7 and 8 (this pH value is automatically adjusted during aeration of the water)
When the concentration of calcium- and/or magnesium-ions in the available water is to high (>3 mmol/l and/or >18 °d), it has to be adjusted by diluting with deionized water.
When the ion concentration is to low (<2 mmol/l and/or. >12 °d), it has to be adjusted by adding a calcium-and/or. magnesium solution.
When the acid capacity is to high, 1 N sulifc acid is added to the water in an in appropriate quantity.
When the acid capacity is to low, 1 M hydrogencarbonate solution is added to the water in an appropriate quantity. - Test organisms (species):
- Leuciscus idus melanotus
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- No data
- Test temperature:
- No data
- pH:
- No data
- Dissolved oxygen:
- No data
- Salinity:
- No data
- Conductivity:
- No data
- Nominal and measured concentrations:
- No data
- Details on test conditions:
- No data
- Reference substance (positive control):
- yes
- Remarks:
- recommended by test protocol but not specified in text
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC0
- Effect conc.:
- 250 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 325 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC100
- Effect conc.:
- 400 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC0
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 160 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC100
- Effect conc.:
- 250 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- No data
- Results with reference substance (positive control):
- No data
- Reported statistics and error estimates:
- No data
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 48 h LC50 values were 160 and 325 mg/l
- Executive summary:
Goldfish were exposed to oxalic acid during 48 h according to guideline Deutsche Einheitsverfahren zur Wasser, Abwasser und Schlamm-Untersuchung L 15 Fischtest. A 48 h LC0 of 100 and 250 mg/l was determined. The 48h LC0 values were 100 and 250 mg/l, 48 h LC50 values were 160 and 325 mg/l and the 48 h LC100 values were 250 and 400 mg/l.
Reference
Description of key information
Goldfish were exposed to oxalic acid during 48 h. The 48h LC0 values were 100 and 250 mg/l, 48 h LC50 values were 160 and 325 mg/l and the 48 h LC100 values were 250 and 400 mg/l.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 160 mg/L
Additional information
A 48 h toxicity and a 96 h toxicity test was carried out. Although generally preference would be given to 96 h toxicity tests for short term toxicity to fish, in this case the 48h toxicity test was selected, because: a) this was the best test (best described) and b) the observed LC50 was the lowest observed value
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