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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
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Diss Factsheets
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EC number: 203-453-4 | CAS number: 107-02-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Freshwater fish
60 d NOEC=0.0114 mg/L (measured; basis for effects: mortality of adults, number of spawning, number of eggs per female, number of eggs per spawn, length of offspring and hatchability)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.011 mg/L
Additional information
1. European Union Risk Assessment Report of Acrolein (EU, 2001)
Fresh water
(EU, 2001) literal citation: “In addition to the base set information for fish, also a long-term NOEC-value is available. In a 60-days reproduction study with Pimephales promelas a NOEC-value of 11.4 μg/l is reported (measured value) for effects on mortality of adults, number of spawning, number of eggs per female, number of eggs per spawn, length of offspring and hatchability.”
Marine fish
(EU, 2001) literal citation: “Long-term toxicity data for marine fish species are not available.”
2. Agreement with further international Reports and Studies published after finalisation of the EU Risk Assessment Report 2001
WHO (2002): Acrolein was toxic to the fathead minnow (Pimephales promelas) following a 60-day exposure to 21.8 μg/litre. The survival of the F1 fathead minnow was significantly reduced at 42 μg/litre; the NOEL for F1 survival was estimated to be 11 μg/litre.
3. Substantial disagreements in comparison to further international Reports to European Union Risk Assessment Report 2001
None
4. Additional aspects in further international Reports
None
5. Additional information in newer Studies, not included in the European Union Risk Assessment Report 2001 or further cited international reports
None
6. Conclusions
The lowest reliable long-term fish toxicity study is a 60-days reproduction study with Pimephales promelas. A NOEC-value of 11.4 μg/l is reported (measured value) for effects on mortality of adults, number of spawning, number of eggs per female, number of eggs per spawn, length of offspring and hatchability.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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