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Diss Factsheets
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EC number: 211-471-9 | CAS number: 646-25-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu./o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_environmental-fate-and-pathways.png)
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2011-12-05 to 2011-05-20
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study; restriction: result slightly outside range of applicability stated in guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Version / remarks:
- (2001)
- Deviations:
- yes
- Remarks:
- (result 5.2 slightly outside range 1.5 - 5.0)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Version / remarks:
- (2008)
- Deviations:
- yes
- Remarks:
- (result 5.2 slightly outside range 1.5 - 5.0)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- soil/sewage sludge
- Radiolabelling:
- no
- Test temperature:
- ambient (buffered test: 24.0 to 24.9 °C; unbuffered test: 23.8 to 24.8 °C)
- Details on study design: HPLC method:
- Apparatus: HPLC System HP 1100 (Agilent) with refractometer HP 1100 (Agilent)
HPLC conditions:
Stationary phase: Zorbax CN, 250 x 4 mm, 5 µm
Mobile phase (eluent):
- buffered testing:
methanol / buffer (pH 7.5) 65/35 (v/v)
(buffer: 16 ml 0.2 mol NaH2PO4 + 84 ml 0.2 mol Na2HPO4/ 1 l purified water; adjusted to pH 7.5 with H3PO4)
- dissociated testing:
methanol / purified water (pH 6.3) 65/35 (v/v)
Flow rate: 1.0 ml/min
Injection volume: 20 µl
Detection: refractive index
Urea was used as dead time marker.
Evaluation: external standard method
Reference compounds:
No. Reference sub. Purity (meth.) Weight / solvent
0 Urea 99.8 % (DSC) 25.52 mg / 25 ml eluent
1 Acetanilide 100 % (HPLC) 23.06 mg / 25 ml solvent 1
2 Monuron 99.9 % (HPLC) 20.50 mg / 25 ml solvent 1
3 Triapenthenol > 99 % 20.03 mg / 25 ml solvent 1
4 Linuron 99.7 % (HPLC) 21.52 mg / 25 ml solvent 1
5 Fenthion 96.2 % (HPLC) 22.22 mg / 25 ml solvent 1
6 Trifluralin 99.2 % (GC) 20.64 mg / 25 ml solvent 1
7 Phenanthrene 99.2 % (HPLC) 21.72 mg / 25 ml solvent 2
8 4,4’-DDT 99.2 % (GC) 20.17 mg/ 25 ml solvent 2; only used for unbuffered testing
Solvent 1: methanol / water (purified) 65/35 (v/v)
Solvent 2: 23 ml methanol + 2 ml purified water - Type:
- Koc
- Value:
- 125 893
- Temp.:
- 25 °C
- Remarks on result:
- other: buffered at pH 7.5
- Type:
- log Koc
- Value:
- 5.1
- Temp.:
- 25
- Remarks on result:
- other: buffered at pH 7.5
- Validity criteria fulfilled:
- yes
- Conclusions:
- The adsorption coefficient on soil and on sewage sludge (Koc) of decamethylenediamine was determined according to OECD guideline 121 [2001] and EU test method C.19 [2008]. The result was log Koc = 5.1 (Koc = 125893) at pH 7.5 and 24.0-24.9 °C, indicating "very high" sorption potential (Blume scale). The test substance was not eluted when tested without buffer.
- Executive summary:
The adsorption coefficient on soil and on sewage sludge (Koc) of decamethylenediamine was determined according to OECD guideline 121 [2001] and EU test method C.19 [2008]. The result was log Koc = 5.1 (Koc = 125893) at pH 7.5 and 24.0-24.9 °C, indicating "very high" sorption potential (Blume scale). The test substance was not eluted when tested without buffer.
Reference
Summary of the results of the HPLC measurements of the reference compounds and the test item (buffered testing):
Sample no.1) |
tR1 [min] |
tR2 [min] |
tR [min] |
k’ |
log k’(x) |
log KOC(y) |
0 |
2.52 |
2.52 |
2.52 |
--- |
--- |
--- |
1 |
2.93 |
2.94 |
2.94 |
0.167 |
-0.777 |
1.25 |
2 |
3.30 |
3.30 |
3.30 |
0.310 |
-0.509 |
1.99 |
3 |
3.59 |
3.59 |
3.59 |
0.425 |
-0.372 |
2.37 |
4 |
4.02 |
4.01 |
4.02 |
0.595 |
-0.225 |
2.59 |
5 |
5.10 |
5.10 |
5.10 |
1.024 |
0.010 |
3.31 |
6 |
6.69 |
6.68 |
6.68 |
1.651 |
0.218 |
3.94 |
7 |
5.41 |
5.40 |
5.41 |
1.147 |
0.060 |
4.09 |
8 |
7.72 |
7.71 |
7.72 |
2.063 |
0.314 |
5.63 |
log Koc of test substance: |
||||||
Test item |
15.01 |
|
|
4.956 |
0.695 |
5.147 |
Test item |
|
15.04 |
|
4.968 |
0.696 |
5.150 |
Mean value |
|
|
|
|
|
5.1 |
1) For the names of the reference compounds see test conditions.
For the test evaluation the data of the calibration items 7 and 8 were not taken into account because of their poor correlation with the results of the other calibration items.
Summary of the results of the HPLC measurements of the reference compounds and the test item (unbuffered testing):
Sample no.1) |
tR1 [min] |
tR2 [min] |
tR [min] |
k’ |
log k’(x) |
log KOC(y) |
0 |
2.52 |
2.52 |
2.52 |
--- |
--- |
--- |
1 |
2.94 |
2.94 |
2.94 |
0.167 |
-0.777 |
1.25 |
2 |
3.29 |
3.30 |
3.30 |
0.320 |
-0.509 |
1.99 |
3 |
3.61 |
3.62 |
3.62 |
0.437 |
-0.360 |
2.37 |
4 |
4.00 |
4.01 |
4.01 |
0.591 |
-0.228 |
2.59 |
5 |
5.07 |
5.09 |
5.08 |
1.016 |
0.007 |
3.31 |
6 |
6.62 |
6.65 |
6.64 |
1.635 |
0.214 |
3.94 |
7 |
5.38 |
5.37 |
5.38 |
1.135 |
0.055 |
4.09 |
log Koc of test substance: |
||||||
Test item |
- |
|
|
- |
- |
- |
Test item |
|
- |
|
- |
- |
- |
Mean value |
|
|
|
|
|
- |
1) For the names of the reference compounds see test conditions.
For the test evaluation the data of the calibration item 7 were not taken into account because of their poor correlation with the results of the other calibration items.
The test item was not eluted under dissociated conditions. Therefore, log Koc could not be determined.
Description of key information
The adsorption coefficient on soil and on sewage sludge (Koc) of decamethylenediamine was determined according to OECD guideline 121 [2001] and EU test method C.19 [2008]. The result was log Koc = 5.1 (Koc = 125893) at pH 7.5 and 24.0-24.9 °C, indicating "very high" sorption potential (Blume scale). The test substance was not eluted when tested without buffer.
Key value for chemical safety assessment
- Koc at 20 °C:
- 125 893
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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