Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Principles of method if other than guideline:
This study was performed in order to estimate the distribution coefficient log Pow of the test item using HPLC. The HPLC method covers log Pow in the range of 0 to 6. Experimental data (retention times of peaks of the test item and of the reference items) are used together with literature values for the log Pow of the reference items to calculate the log Pow for the test item.
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
6,6'-diphenylfulvene
EC Number:
218-533-4
EC Name:
6,6'-diphenylfulvene
Cas Number:
2175-90-8
Molecular formula:
C18H14
IUPAC Name:
1,1'-(cyclopenta-2,4-dien-1-ylidenemethylene)dibenzene

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
3.43
Remarks on result:
other: no information on temperature and pH available

Applicant's summary and conclusion

Conclusions:
The logPow of the test material has been determined to be 3.43. The study was performed similar to OECD 117 (no GLP) on the substance to be registered itself, the test procedure is well documented and therefore reliability of Klimisch 2 has been assigned.
Executive summary:

The partition coefficient of the test item was determined in a non GLP study similar to OECD 117. Using the HPLC method, The log Pow of the test item was determined to be 3.43.