Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 234-014-5 | CAS number: 10489-46-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu./o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Toxicity to terrestrial arthropods
Administrative data
- Endpoint:
- toxicity to terrestrial arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Not GLP compliant. Minimum number of test concentrations. No details of analytical verification of the test material concentrations.
Data source
Reference
- Reference Type:
- publication
- Title:
- Impact of platinum group elements on the soil invertebrate Enchytraeus crypticus
- Author:
- Havelkova. B et al.
- Year:
- 2 014
- Bibliographic source:
- Neuroendocrinology Letters 35 (2) 101–108
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: ISO 16387 OECD 220
- GLP compliance:
- no
- Application method:
- soil
Test material
- Reference substance name:
- Rhodium trichloride
- EC Number:
- 233-165-4
- EC Name:
- Rhodium trichloride
- Cas Number:
- 10049-07-7
- Molecular formula:
- Cl3Rh
- Test material form:
- other: solution
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test substrate
- Details on preparation and application of test substrate:
- nominal concentrations 50, 100, 150, 200 and 250 μmol/L RhCl3
Test organisms
- Test organisms (species):
- other: Enchytraeus crypticus
- Animal group:
- other: Soil dewelling worm
- Details on test organisms:
- Originated in cultures from the Ecotoxicological laboratory of the University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic.
Study design
- Study type:
- laboratory study
- Limit test:
- yes
- Total exposure duration:
- 28 d
Test conditions
- Test temperature:
- 20±2 °C
- pH (if soil or dung study):
- 6.0±0.5
- Humidity:
- 50% soil moisture
- Photoperiod and lighting:
- 16:8 (light/dark) photoperiod
- Details on test conditions:
- Within each vessel, ten adult enchytraeids of approximately the same size, with eggs in the clitellum region were placed in 20g soil. As food supply, finely ground rolled oats were added. Additional food and water were added when required.
- Nominal and measured concentrations:
- nominal concentrations 50, 100, 150, 200 and 250 μmol/L RhCl3
- Reference substance (positive control):
- yes
- Remarks:
- Boric acid
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 28 d
- Dose descriptor:
- EC50
- Effect conc.:
- 246.2 other: μmol/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Duration:
- 28 d
- Dose descriptor:
- LC50
- Effect conc.:
- 247.2 other: μmol/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Key result
- Duration:
- 28 d
- Dose descriptor:
- EC50
- Effect conc.:
- 48.3 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Basis for effect:
- reproduction
- Remarks on result:
- other: self calculated using Trap v1.30a
- Key result
- Duration:
- 28 d
- Dose descriptor:
- EC10
- Effect conc.:
- 32.7 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Basis for effect:
- reproduction
- Remarks on result:
- other: self estimated using Trap v1.30a
- Details on results:
- A significant effect on mortality and reproduction was observed.
- Results with reference substance (positive control):
- boric acid EC50 150– 170 mg/kg dry weight soil
- Reported statistics and error estimates:
- One-way analysis of variance (ANOVA) and post-hoc analysis of means by the LSD test.
Levene’s method was used to test for the homogeneity of variances.
Non-homogenous parameters were log-transformed prior to analysis and compared with the non-parametric Kruskal-Wallis test.
Any other information on results incl. tables
Concentrations RhCl3(μmol/L) |
No. adult |
Mortality (%) |
No. juveniles produced (mean ± SD) |
CV (%)
|
Inhibition of reproduction (%) |
|
at the beginning of the test |
at the end of the test |
|||||
50 |
10 |
10 |
0 |
128.8±16.5 |
13 |
1 |
100 |
10 |
9.2 |
8 |
126.0±21.8 |
17 |
3 |
150 |
10 |
9 |
10 |
124.4±17.7 |
14 |
4 |
200 |
10 |
6.2 |
38 |
95.2±15.7 |
16 |
27 |
250 |
10 |
4.4 |
56 |
60.6±26.7 |
44 |
53 |
reported | 28d EC50 | 247.2 |
recalculated | EC10 | 164.7 |
EC50 | 243.5 |
RhCl3 (micromol/L) | Rh (micromol/L) | Rh (microg/L) | Rh (mg/L) | Rh (mg/kg ww) | Rh (mg/kg dw) | ||
EC10 | 164.7 | 81.0 | 8335.3 | 8.3 | 28.9 | 32.7 | |
EC50 | 243.5 | 119.7 | 12323.3 | 12.3 | 42.8 | 48.3 | |
MW RhCl3 | 209.26 | 2.033427 | |||||
MW Rh | 103 | ||||||
Kd soil | 3.8 | L/kg | |||||
Ksoil-water | 5.9 | m3/m3 | |||||
RHOsolid | 1700 | kg/m3 | |||||
Dry weight conversion | 1.13 |
Applicant's summary and conclusion
- Conclusions:
- Rhodium trichloride was shown to have a significant effect on the reproduction and mortality of Enchytraeus crypticus under the chosen test conditions. The 28 day EC50 was reported to be 246.2 μmol/L with the inhibition of reproduction at 53% when the organisms were exposed to 250 μmol/L . The study was not conducted according to GLP and has a reliability rating of 2 (reliable with restrictions). The EC10 and EC50 values were recalculated to be 32.7 and 48.3 mg Rh/kg dw, respectively.
- Executive summary:
The influence of rhodium trichloride on the reproduction and mortality of the species Enchytraeus crypticus was investigated according to OECD Test Guideline 220, "CSN EN ISO 16387 – Soil quality – Effects of pollutants on Enchytraeidae (Enchytraeus sp.) – Determination of effects on reproduction". Test specimens were placed in synthetic soil treated with nominal rhodium trichloride concentrations of 50, 100, 150, 200, 250 umol/L. The experiments were carried out with five replicates. The 28 day EC50 for rhodium trichloride was found to be 246.2 umol/L. When the Enchytraeus crypticus were exposed to 250 umol/L rhodium trichloride, the inhibition of reproduction was 53%. A significant effect of mortality was also observed. The EC10 and EC50 values were recalculated to be 32.7 and 48.3 mg Rh/kg dw, respectively.
This study has a reliability rating of 2 (reliable with restrictions) as there is no evidence of analytical verification of test material concentrations. The study was not conducted according to GLP with only the minimum number of test concentrations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)