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Diss Factsheets
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EC number: 604-721-7 | CAS number: 150114-71-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 30 September 2015 to 26 October 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 187
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
- Type of distribution:
- volumetric distribution
- Key result
- Percentile:
- D50
- Mean:
- 18 µm
- Remarks on result:
- other: based on volume (%); 0.46 µm based on number (%) (No source field for Standard deviation.)
- Percentile:
- D10
- Mean:
- 2.3 µm
- Remarks on result:
- other: based on volume (%)
- Percentile:
- D10
- Mean:
- 0.34 µm
- Remarks on result:
- other: based on number (%)
- Percentile:
- D90
- Mean:
- 65 µm
- Remarks on result:
- other: based on volume (%)
- Percentile:
- D90
- Mean:
- 0.75 µm
- Remarks on result:
- other: based on number (%)
- Conclusions:
- Under the conditions of the study, the 50 % quantile from the particle size distribution assessment of the test material was 18 µm based on the percentage volume and 0.46 µm based on the percentage number.
- Executive summary:
The particle size distribution of the test material was assessed in a study conducted in accordance with the standardised guideline CIPAC MT 187 under GLP conditions.
The size distribution of particles was assessed using particle size apparatus based on laser diffraction. Duplicate portions of the test material (approximately 45 mg) were dissolved in the chloroform dispersant (10 mL) and the resulting mixtures were shaken and transferred to the sampling tank. The samples were then sonicated for 1 minute prior to measurement. For each sample, two measurements were taken 20 seconds apart and the mean data was calculated.
The morphology of the particles was assessed under a microscope and the sample of test material was found to consist of a combination of irregular crystalline particles and cylindrical structures.
Under the conditions of the study, the 50 % quantile from the particle size distribution assessment of the test material was 18 µm based on the percentage volume and 0.46 µm based on the percentage number.
Reference
Table 1: A summary of the 10, 50 and 90 % quantile results
Quantile |
Size (µm) |
|
Based on volume (%) |
Based on number (%) |
|
d(0.1) |
2.3 |
0.34 |
d(0.5) |
18 |
0.46 |
d(0.9) |
65 |
0.75 |
The morphology of the particles was assessed under a microscope and the sample of test material was found to consist of a combination of irregular crystalline particles and cylindrical structures.
The 50 % quantile from the particle size distribution assessment of the test material was 18 µm based on the percentage volume and 0.46 µm based on the percentage number.
Description of key information
MMD = 18 µm (based on percentage volume) and 0.46 µm (based on percentage number), CIPAC MT 187, Comb (2015)
Additional information
The particle size distribution of the test material was assessed in a study conducted in accordance with the standardised guideline CIPAC MT 187 under GLP conditions. The study was assigned a reliability score of 1 in line with the criteria of Klimisch et al. (1997).
The size distribution of particles was assessed using particle size apparatus based on laser diffraction.
Under the conditions of the study, the 50 % quantile from the particle size distribution assessment of the test material was 18 µm based on the percentage volume and 0.46 µm based on the percentage number.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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