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Diss Factsheets
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EC number: 424-510-1 | CAS number: 220150-59-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48 hours, Daphnia magna) = 49 mg/l (mean measured)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 49 mg/L
Additional information
The toxicity of the test item to invertebrates was evaluated in an experimental study on Daphnia magna according to the OECD Guideline 202 (1984) and the EU Method C.2 (1992). Four groups of 5 Daphnia per flask were exposed to various concentrations of the test item in aqueous test media for 48 hours in a static test under defined conditions, and were monitored daily for imobilisation. The nominal concentrations of test item were 9.2, 20, 42, 92 and 200 mg/l. Flasks were monitored for oxygen concentration, pH level, and behaviour of the test item in test media at the beginning and end of the study period.
In the test media the measured test substance concentrations at the start of the test ranged from 81 % to 98 % of the nominal values. During the test period of 48 hours a slight decrease of test substance concentration in the test media was determined. The mean measured test concentrations (calculated as the average over all measurements per test concentration) varied in the range of 76 % to 96 % of the nominal values. Therefore, the reponed biological results are related to the mean measured test substance concentrations.
Strong colouration of the test media and the Daphnia was observed, caused by the test item. Dissolved oxygen concentration ranged from 8.4 to 10.2 mg/l during the study period. Based on the observations, the EC50 (48 hours) was determined to be 49 mg/l test item at a 95 % confidence interval from 33 to 74 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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