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Diss Factsheets
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EC number: 231-901-9 | CAS number: 7778-39-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Freshwater species
The 48–hr-acute toxicity of Arsenic acid to Daphnia pulex was studied under static conditions. Daphnids were exposed to control, and test chemical at nominal concentrations in mg/L of: control, 0.25; 0.50; 1.0; 2.0; 5.0 mg/l. Immobilization effects were observed at 0h, 1h, 2h, 4h, 6h and daily thereafter. The 48–hr EC50 was 3.26 mg/L, based on the nominal concentrations.
This study is classified as acceptable and satisfies with the guidelines requirements for an acute toxicity study with freshwater invertebrates.
Marine species:
The 48h toxicity of sodium arsenate was tested on the aquatic crustacean Strongylocentrotus purpuratus. The tested concentrations were 0.0023–0.091 mg l-1. Results were expressed in terms of nominal concentrations. On the basis of the data reported, it was possible to derive an EC10 of 6 μg l-1 and an EC50 of 15 μg l-1 based on effects on embryo development.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 3.26 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 6 µg/L
Additional information
Freshwater species
Several toxicity data are available on daphnia short term toxicity.
Beside the key study, a second data is available on Arsenic V short term toxicity to freshwater invertebrates.
The 48–hr-acute toxicity of Arsenic acid to Daphnia magna was studied. Daphnids were exposed to control, and test chemical at nominal concentrations ranged from 29.82 -115.38 mg/L. Mortality was observed. The 48–hr LC50 was 44.66 mg/L, based on the nominal concentrations.
This study is classified as acceptable and satisfies with the guidelines requirements for an acute toxicity study with freshwater invertebrates.
Marine species
Beside the key study, another data as available on marine invertebrates short term toxicity. The 96hr-acute toxicity of Arsenic acid toMysidopsis bahia was studied. Mysids were exposed to control, and test chemical at measured concentrations of 0.0 (control), 0.32, 0.63, 1.2, 1.7, 3.0, 5.2 and 9.0 mg a.i/L. Mortality and biological and physical effects were observed. The 96hr- LC50 was 2 mg/L, based on the measured concentrations.
This study is classified as acceptable and satisfies with the guidelines requirements for an acute toxicity study with freshwater invertebrates.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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