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Diss Factsheets
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EC number: 469-110-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
AD-1000 is not readily biodegradable neither under the conditions of the modified Sturm test nor under the conditions of a head space test.
QSAR's run on both components of the test substance revealed that the the Boethling criteria for ready biodegradation predicted not readily biodegradable whereas the MITI models predicted readily degradability of the substance.
Definitive conclusions with regard to ready biodegradation cannot be drawn from the non-interpretable and non-conclusive results. The substance, however, is deemed to biodegrade fast.
Key value for chemical safety assessment
Additional information
AD-1000 was experimentally tested for biodegradation in two different studies. In a modified Sturm test (according to test guidelines OECD 301 B and EC C.4) with activated sludge under aerobic conditions only 3% degradation of AD-1000 was observed after 28 days. In a head space test (according to test guideline OECD 310) with adapted activated sludge under aerobic conditions 5% degradation of AD-1000 was observed after 28 days. It is thus concluded that AD-1000 is not readily biodegradable under the conditions of the modified Sturm test and the head space test. The results of these tests, however, cannot be interpreted because the tested concentrations in both tests were far above the maximum water solubility. Thus, in view of lack of the optimal contact between the test substance and the medium in the test, no definitive conclusions can be drawn with respect of biodegradability of the test substance.
Further testing for biodegradability by the enhanced ready biodegradation test (ISO Guideline 10634) was deemed to be
technically not possible (see attached letter).The QSAR model EPIWEB was used in order to gain supplementary information on the biodegradability because no definitive conclusions could be drawn with respect of biodegradability of the test substance based on the two experimental screening studies. The validity and applicability criteria, as described in the REACH guidance, of the QSAR estimation were not evaluated in detail. However, BIOWIN is a known and reliable calculation tool for this endpoint. The BIOWIN models revealed no conclusive evidence either on the ready biodegradation, but the estimations indicated that the substance biodegrades fast.
Definitive conclusions with regard to ready biodegradation cannot be drawn from the non-interpretable and non-conclusive results. The substance, however, is deemed to biodegrade fast.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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