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EC number: 237-531-4 | CAS number: 13826-83-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- the study does not need to be conducted because the substance is unlikely to cross biological membranes, hence indicating that aquatic toxicity is unlikely to occur
- Justification for type of information:
- Ammonium tetrafluoroborate is a non-polar salt molecule, of two different ionic parts: NH4 as the cation and BF4 as the anion. It is water soluble and is easily hydrolysed, hence, not likely to pass the biological membrane of fish as ammonium tetrafluoroborate. The ammonium ions are themselves a waste product of the metabolism of animals. In fish and aquatic invertebrates, it is excreted directly into the water. Even the BF4 cation is being hydrolysed in water at room temperature. Research has proven that the toxicity of ionic liquids come from the length of the alkyl chains. Ammonium tetrafluoroborate is an ionic liquid, but it does not contain any alkyl chains on the cation or the anion.
The toxic effects of ionic liquids are directly related to disruption of cell membrane. This is due to long alkyl chains, often presented in the cationic part of ionic liquids, which increase the lipophilic character of the ionic liquids molecule. It has been confirmed that the toxicity of ionic liquids is associated with their lipophilic character and membrane damage. However, ammonium tetrafluoroborate does not contain any lipophilic alkyl chains.
There are results obtained by electrospray ionization mass spectrometry, NMR spectroscopy, and pH measurements that clearly indicate that hydrolysis is a process restricted to ([PF6]- and) [BF4]-, while imidazolium cation remains unchanged. Hydrolysis of [BF4]- was observed under all of the experimental conditions used, even at room temperature.
Apart from ammonium ions, hydrogen fluoride is probably formed when ammonium tetrafluoroborate is being dissolved in aquatic environment. In aqueous form it is called hydrofluoric acid. Hydrogen fluoride is only a weak acid in dilute aqueous solution. This is in part a result of the strength of the hydrogen-fluorine bond, but also of other factors such as the tendency of HF, H2O, and F− anions to form clusters.
Hydrogen fluoride is not included in Reproductive and Developmental Toxicants, a 1991 report published by the U.S. General Accounting Office (GAO) that lists 30 chemicals of concern because of widely acknowledged reproductive and developmental consequences. Fluoride crosses the placenta, and at low doses is thought to be essential for normal fetal development in humans. It is rarely excreted in breast milk. There have been rare cases of mottling of deciduous teeth in infants born to mothers who had high daily intakes of fluoride during pregnancy; skeletal abnormalities are considered unlikely. No reproductive effects due to hydrogen fluoride are known.
It has also been concluded by Slooff (1998) that the limited data available indicate that accumulation through food chains (biomagnification) is of little significance in the aquatic environment.
In one study it was especially noted that in none of the animal carcinogenicity studies effects on morphology of any of the reproductive organs were found. Effects on on the reproduction are systemic and HF occurs in the systemic circulation only as a free ionic or as organically bound fluoride rather tan as HF or NaF. In several studies, the effect of fluoride on the testes of mice, rats and rabbits with respect to reproductive impairment was tested. In none of these studies the fluoride anion content of the control diet was stated. In natural water, fluoride ions form strong complexes with aluminium, and fluorine chemistry in water is largely regulated by aluminium concentration and pH. Below pH 5, fluorine is almost entirely complexed with aluminium and consequently, the concentration of free F- is low. As the pH increases, Al-OH complexes dominate over Al-F complexes and the free F level increases. The dominant Al-F complex at pH <5 is AlF2+) is of little significance in the aquatic environment.
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Reference Type:
- publication
- Title:
- Toxicity mechanisms of ionic liquids.
- Author:
- Marina Cvjetko Bubalo, Kristina Radošević, Ivana Radojčić Redovniković, Igor Slivac, and
Višnja Gaurina Srček - Year:
- 2 017
- Bibliographic source:
- Arh Hig Rada Toksikol, 2017;68:171-179
- Reference Type:
- publication
- Title:
- Hydrolysis of Tetrafluoroborate and Hexafluorophosphate Counter Ions in Imidazolium-Based Ionic Liquids.
- Author:
- Mara G. Freire, Catarina M. S. S. Neves, Isabel M. Marrucho, Joa˜o A. P. Coutinho, and Ana M. Fernandes.
- Year:
- 2 009
- Bibliographic source:
- J. Phys. Chem. A 2010, 114, 3744–374
- Reference Type:
- review article or handbook
- Title:
- Kirk-Othmer Encyclopedia of Chemical Technology. 4th ed. Volumes
- Year:
- 1 994
- Bibliographic source:
- Kirk-Othmer Encyclopedia of Chemical Technology. 4th ed. Volumes 1: New York, NY. John Wiley and Sons, 1991-Present., p. V11: 313 (1994)
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.