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EC number: 237-149-8 | CAS number: 13669-76-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
No study data is available for the test
substance. Similar to all coordination complexes of boron trifluoride
with organic and inorganic species (like alcohols, ethers, amines,
sulfuric acid, sulfuric dioxide, etc) the complex of boron trifluoride
and phosphoric acid is extremely water sensitive and reacts even with
moist air. In the instantaneous reaction with water as a first step
phosphoric acid and boron trifluoride dihydrates are formed. The latter
undergoes further rapid hydrolysis to boric acid, fluoboric acid and
tetrafluoroborate. Effects on aquatic algae were studied using the read
across substances boric acid (CAS No 10043-35-3), phosphoric acid (CAS
No 7664 -38 -2) and tetrafluoroborate.
WoA (phosphoric acid; study report 2010)
In a 96 -hour toxicity study, cultures of green algae (Desmodesmus
subspicatus) were exposed to the read across substance phosphoric acid
(CAS No 7664 -38 -2) a nominal concentration of 100 mg/L under static
conditions according to OECD guideline 201. The concentration used for
the main test was based on a preliminary test conducted with nominal
concentrations of 0.10, 1.0, 10 and 100 mg/L. No effects on growths were
observed up to 10 mg/L. The growth was slightly reduced at 100 mg/L.
In the main test the pH value of the test concentration was adjusted to
7.5 and six replicates were tested. No growth inhibition was observed in
any of the replicates. Furthermore no abnormalities were observed. The
NOEC and EC50 values based on algae growth were 100 mg/L and > 100 mg/L.
WoA (Public references I and II from 1965 to 1990 and from 1980 to
2002; focus on boron)
NOEC(4d) values, obtained for the fresh water algae Chlorella
pyrenoidosa (10 mg B/L), Anacystis nidulans (50 mg B/L) and EC10(3d)
values obtained from fresh water algae Selenastrum capricornutum (24.5
mg B/L, biomass; 35 mg B/L; growth rate) are reported and applicable
assessing the read across substance boric acid (CAS No 10043-35-3).
Another non published data according to OECD 201 with Selenastrum
capricornutum (Hanstveit and Oldersma 2000) reported a NOEC
concentration of 17.5 mg B/L. The lowest NOEC value was found in the
fresh water algae Chlorella pyrenoidosa (0.4 mg B/L) after 14 days study
duration which does not meet the standard procedure. Finally, the
EC50(4d) value obtained for the fresh water algae Selenastrum
capricornutum of 3.3 mg B/L (growth rate) is regarded as worst case
result.
WoE (tetrafluoroborate)
In the present study, the toxic effects of imidazolium-based ILs
(1-butyl-3-methylimidazolium cation associated with bromide [BMiM][Br]
and tetrafluoroborate [BMIM][BF4]) to the freshwater green alga
Selenastrum capricornutum were investigated. Two approaches were
followed to quantify toxicity of these compounds: Analyses of
photosynthetic activity and cell proliferation. The obtained data showed
that the relative declines of growth rates generally were more
pronounced than those of photosynthetic activity. The ecotoxicity of a
range of common organic solvents also was examined. It was revealed that
both imidazolium-based ILs studied were some orders of magnitude more
toxic than methanol, isopropanol, and dimethylformamide ([BMIM][BF4
]EC50 was estimated 3467µM resulting in approx. 784 mg/L). In addition,
with respect to incorporating perfluorinated anion, EC50 values of the
previously prepared stock solution were significantly lower compared to
those of the freshly made one. This might be due to hydrolytic effects
of [BMIM][BF4] leading to fluoride formation. which was confirmed by ion
chromatography analysis.
Based on the results of the acute ecotoxicity tests using freshwater
algae, the EC50(96h) of > 100 mg/L for phosphoric acid does not
indicate toxicity triggering classification and labelling. Boric acid
reveals NOEC(4d) and EC10(3d) values of about 10 to 50 mg B/L. The
EC50(4d) value with boric acid obtained for the fresh water algae
Selenastrum capricornutum of 3.3 mg B/L (growth rate) is regarded as
worst case result (considering the molecular weight ratio of boron
trifluoride phosphoric acid complex versus boron, the EC50/(4d) would be
50 mg boron trifluoride phosphoric acid complex/L) but would not
trigger classification and labelling for boric acid as all (chronic)
NOEC values are > 1 mg/L and the substance has no potential to
bioaccumulate. With respect to aquatic toxicity, boric acid is not
classified according to Dangerous Substance Directive 1272/2008 (CLP).
In conclusion, the substance boron trifluoride phosphoric acid complex
needs not to be classified and labelled as under Regulation (EC) No
1272/2008, as amended for the sixth time in Regulation EC No 605/2014.
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