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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 231-901-9 | CAS number: 7778-39-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu./o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Toxicity to soil microorganisms
Administrative data
- Endpoint:
- toxicity to soil microorganisms
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: The study is aimed to obtain fungi growth inhibition in the presence of arsenate. Therefore, the concentrations used for this purpose are very high and do not allow to obtain any regulatory endpoint.
Data source
Reference
- Reference Type:
- publication
- Title:
- Variation in the toxicity of arsenic compounds to microorganisms and the suppression of the inhibitory effects by phosphate
- Author:
- DaCosta EWB
- Year:
- 1 972
- Bibliographic source:
- Applied Microbiology 23(1): 46-53
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The growth of fungi on agar containing various concentrations of arsenic.
Test material
- Reference substance name:
- Arsenate
- IUPAC Name:
- Arsenate
- Details on test material:
- Potassium arsenate was produced by reacting arsenic pentoxide dihydrated (As2O5.2H2O) with KOH to give an analogous pH of 4.4
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test substrate
- Vehicle:
- no
- Details on preparation and application of test substrate:
- The arsenate-nutrient media were prepared by autoclaving separately: (i) the appropriate solutions of potassium arsenate and (ii) the nutrient medium.
Test organisms
- Test organisms (inoculum):
- other: Various fungus
Study design
- Total exposure duration:
- 8 wk
Test conditions
- Test temperature:
- 27°C
- Moisture:
- Not applicable (agar cultivation medium)
- Details on test conditions:
- TEST SYSTEM
- Test container (type, material, size): screwed-capped glass phials
- Amount of substrate: agar strip 90 mm long, 25 mm wide and up to 3 mmdeep
- No. of replicates per concentration: 2
- No. of replicates per control: 2
SUBSTRATE INCUBATION
- Method: series of individual subsamples
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : growth - Nominal and measured concentrations:
- 0, 0.005 M, 0.02 M, 0.08 M (i.e., 0, 0.375, 1.50, and 5.99 g/l)
- Reference substance (positive control):
- no
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 8 wk
- Dose descriptor:
- EC100
- Effect conc.:
- <= 0.005 other: M
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: growth
- Remarks on result:
- other: Poria monticola (no growth at any As concentration)
- Duration:
- 8 wk
- Dose descriptor:
- EC100
- Effect conc.:
- <= 0.005 other: M
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: growth
- Remarks on result:
- other: Poria cocos (no growth at any As concentration)
- Duration:
- 8 wk
- Dose descriptor:
- EC100
- Effect conc.:
- >= 0.08 other: M
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: growth
- Remarks on result:
- other: Poria vaillantii
- Duration:
- 8 wk
- Dose descriptor:
- EC100
- Effect conc.:
- <= 0.005 other: M
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: growth
- Remarks on result:
- other: Coniophora olivacea (no growth at any As concentration)
- Duration:
- 8 wk
- Dose descriptor:
- EC100
- Effect conc.:
- >= 0.02 - <= 0.08 other: M
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: growth
- Remarks on result:
- other: Lenzites trabea
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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