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Diss Factsheets
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EC number: 204-633-5 | CAS number: 123-51-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of the test substance on Scenedesmus subspicatus (new name: Desmodesmus subspicatus) was determined according to DIN 38412 part 9 under Non-GLP conditions (BASF 1989). After 72 hours the ErC10 was determined to be 141 mg/L and the EC50 was determined to be greater than 500 mg/L (growth rate) and 493 mg/L (biomass). All values based on nominal concentrations. In addition study results are available for the other category members, revealing EC50 and EC10 values well above 100 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 260 mg/L
Additional information
The toxicity of the test substance on Scenedesmus subspicatus (new name: Desmodesmus subspicatus) was determined according to DIN 38412 part 9 under Non-GLP conditions (BASF 1989). After 72 hours the ErC10 was determined to be 141 mg/L and the EC50 was determined to be greater than 500 mg/L (growth rate) and 493 mg/L (biomass). All values based on nominal concentrations
In addition, a read across category approach was done to the other category members.
The toxicity of the surrogate test substance pentanol, branched and linear (CAS 94624-12-1) to the freshwater alga Pseudokirchneriella subcapitata was determined according to the principles of OECD 201 under GLP conditions (BASF 2011). The aim of the study was to assess the effects on growth rate and yield over a period of 72 hours. After 72 hours the NOEC, the EC10 and the EC50 were determined to be greater than 320 mg/L.
Furthermore, the toxicity of the surrogate test substance 2-methylbutan-1-ol to the freshwater alga Pseudokirchneriella subcapitata was determined also according to the principles of OECD 201 under GLP conditions (BASF 2011). After 72 hours the NOEC was determined to be 29 mg/L, the ErC10 was determined to be 132 mg/L and the ErC50 was determined to be greater than 353 mg/L. All values based on measured concentrations.
Supplementary a publication (Bringmann et al. 1977) is available describing the influence of the read across substance pentan-1-ol on the growth of the freshwater algae Scenedesmus quadricauda. The study was conducted under static conditions. The 8 days EC50 was determined to be 260 mg test item/L. No EC10 value is available from this study.
In conclusion, the 72h-EC50 and the 72h-EC10 value of the test substance and of the read across category members was determined to be greater than 100 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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